Results 81 to 90 of about 602,192 (314)

Spatially regularized estimation for the analysis of DCE-MRI data [PDF]

, 2012
Competing compartment models of different complexities have been used for the quantitative analysis of Dynamic Contrast-Enhanced Magnetic Resonance Imaging data.
Gertheiss, Jan, Schmid, Volker J., Sommer, Julia C.   +2 more
core   +1 more source

Effects of dietary incorporation of Moringa oleifera leaf meal on hatching characteristics and serum parameters of local Guinea fowl (Numida meleagris) in Togo

Journal of Advanced Veterinary and Animal Research
Objective: This study investigated the effects of local guinea fowl breeder's diet incorporation with Moringa oleifera leaf powder on the hatching rate, quality and serum parameters of keet in Togo.
Patrik Nukunu Komi Atitso, Kokou Voemesse, Aduayi Akue, Hèzouwè Tchilabalo Meteyake, Kafui Amivi Tete-Benissan   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Prediction blood pressure parameter by using neuro-fuzzy model [PDF]

, 2013
Blood pressure is the most often measured and intensively studied in medical and physiological practice because it is the valuable diagnostic aid to access the vascular condition of certain illnesses.
Fahmi Ariaff, Mohd. Faizz
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Laboratory analyses for evaluation of platelet disorders and platelet concentrates

, 2006
High quality of platelet analytics requires specialized knowledge and skills. It was applied to analyze platelet activation and aggregation responses in a prospective controlled study of patients with Finnish type of amyloidosis.
Javela, Kaija
core  

Growth Performance, Organ Weights and Some Blood Parameters of Replacement Laying Pullets Fed with Increasing Levels of Wheat Bran

Brazilian Journal of Poultry Science, 2015
This study was conducted to determine the growth performance, organ weights, and selected blood parameters of replacement laying pullets (development phase) fed increasing levels of wheat bran (WB).
Y Martínez, Y Carrión, R Rodríguez, M Valdivié, C Olmo, C Betancur, G Liu, NA Al-Dhabi, V Duraipandiyan   +8 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Parameter estimates for the models of target cell kinetics in blood and spleen.

, 2014
Parameter estimates for the models of target cell kinetics in blood and spleen.
Andrew Yates (29428), Ulrich Kadolsky (241194), Sim Tung (631182), Thea Hogan (631181), Benedict Seddon (170494)   +4 more
core   +1 more source