Results 181 to 190 of about 629,937 (377)

Associations of white blood cell and platelet counts with specific depressive symptom dimensions in patients with bipolar disorder: Analysis of data from the FACE-BD cohort

open access: bronze, 2022
Aistė Lengvenytė   +18 more
openalex   +2 more sources

BMQ [PDF]

open access: yes, 1963
BMQ: Boston Medical Quarterly was published from 1950-1966 by the Boston University School of Medicine and the Massachusetts Memorial ...
Antuna, Juan   +25 more
core  

Rapamycin Alleviates Heart Failure Caused by Mitochondrial Dysfunction and SERCA Hypoactivity in Syntaxin 12/13 Deficient Models

open access: yesAdvanced Science, EarlyView.
Rapamycin alleviates heart failure via TFEB and CaMKII pathways in Syntaxin 12/13 deficient models. Stx12 deficiency causes heart failure via impaired iron trafficking to mitochondria, reducing respiratory complexes and sarcoplasmic reticulum Ca2+‐ATPase (SERCA).
Run‐Zhou Yang   +12 more
wiley   +1 more source

PO03 | Enlarged platelets with reduced GP IB/IX can indicate disorders other than Bernard-Soulier syndrome

open access: yesBleeding, Thrombosis and Vascular Biology
Background and Aims: Evaluation of platelet morphology is a cornerstone of the diagnostic work-up of patients with suspected inherited platelet disorders (IPD).
doaj   +1 more source

Inhibition of FOXM1 Synergizes with BH3 Mimetics Venetoclax and Sonrotoclax in Killing Multiple Myeloma Cells through Repressing MYC Pathway

open access: yesAdvanced Science, EarlyView.
Relapsed and refractory multiple myeloma remains a major clinical challenge. This study shows that FOXM1 contributes to resistance against BH3 mimetics in multiple myeloma cells. The FOXM1 inhibitor NB73 enhances the effectiveness of BH3 mimetics by reducing FOXM1 expression and suppressing the MYC pathway.
Zhi Wen   +16 more
wiley   +1 more source

Rola szlaku CD40/CD40L w biologicznej aktywności płytek krwi. Część I

open access: yesMenopause Review, 2010
The main function of blood platelets is their haemostatic role, but recent evidence shows that processes of platelet activation may be sometimes a critical link between haemostasis and development of inflammation.
Karolina Królewska   +1 more
doaj  

Regulating Enzyme Activity via Microaggregates Mediated by Phase Separation

open access: yesAdvanced Science, EarlyView.
An enzyme‐sequestration strategy for combating postoperative pancreatic fistula (POPF) is developed, employing a D‐peptide called DPMD to induce liquid–solid phase separation (LSPS) of pancreatic proteases. This LSPS‐driven microaggregate approach effectively isolates trypsin and chymotrypsin from their substrates, thereby reducing pancreatic fluid ...
Yang Wang   +7 more
wiley   +1 more source

Platelet function tests: a comparative review

open access: yesVascular Health and Risk Management, 2015
Rita Paniccia,1,2 Raffaella Priora,1,2 Agatina Alessandrello Liotta,2 Rosanna Abbate1,2 1Department of Experimental and Clinical Medicine, Thrombosis Center, University of Florence, Florence, Italy; 2Department of Heart and Vessels, Azienda Ospedaliero ...
Paniccia R   +3 more
doaj  

Artificial Intelligence‐Driven Proteomics Identifies Plasma Protein Signatures for Diagnosis and Stratification of Behçet's Disease

open access: yesAdvanced Science, EarlyView.
Molecular and functional landscape of BD progression and severity based on in‐depth proteomics. Tree boosting machine learning models with favorable performance in BD diagnosis and stratification. Efficient biomarker panels for BD diagnosis and stratification. .
Linlin Cheng   +6 more
wiley   +1 more source

Tendon Aging: A Silent Enemy Revealed Strategies for Effective Treatment

open access: yesAGING MEDICINE, EarlyView.
This review commences with the mechanism of tendon aging, mainly introducing the aging of tendons induced by oxidative stress, hyperglycemia, inflammatory response, cell apoptosis, and fatty infiltration and the association with the tendon stem/progenitor cells, aiming to explore the mechanism of aging and find related treatment methods.
Wenhui Gu   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy