Results 191 to 200 of about 283,642 (353)

Phocaeicola coprophilus‐Derived 6‐Methyluracil Attenuates Radiation‐Induced Intestinal Fibrosis by Suppressing the IDO1‐Kynurenine‐AHR Axis

Advanced Science, EarlyView.
IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang, Zhen Wang, Shuang Li, Chao Luo, Han Li, Shengjie Ma, Pai Wang, Heshi Liu, Lijun Sun, Yue Yin, Weizhen Zhang, Quan Wang   +11 more
wiley   +1 more source

A Retrospective Analysis of Blood Component Utilization and Transfusion-Related Factors in a Diverse Patient Population. [PDF]

Healthcare (Basel)
Almujali YA, Darwish NM, Ba Abbad AA, Tamim H, Sajid MR, Saleem RA, Binjomah A, Aldosari K.   +7 more
europepmc   +1 more source

Micro‐Organ Chip Deciphers Tumor‐Derived G‐CSF as Remote Commander of Lung Pre‐Metastatic Niche via VEGFA‐KDR Cascade

Advanced Science, EarlyView.
Breast cancer reprograms the lung into a receptive pre‐metastatic niche via a novel G‐CSF–VEGFA–KDR signaling axis. Using a micro‐organ chip that enables contact‐independent coculture, this study uncovers how tumor‐secreted G‐CSF activates lung capillary KDR to drive angiogenesis and prime the soil for metastasis—without direct tumor contact.
Jingxin Zhang, Xiaoying Huang, Lingchuan Ma, Zixing Chen, Tianyao Li, Lijian Wang, Yutong Guo, Hu Xu, Junqi Li, Jiang‐Jiang Qin, Xiang Wang, Yuhong Cao, Kai Miao   +12 more
wiley   +1 more source

Acquired platelet disorders. [PDF]

Front Med (Lausanne)
Altahan RM.
europepmc   +1 more source

Thrombosis and bleeding in myeloproliferative disorders: identification of at‐risk patients with whole blood platelet aggregation studies [PDF]

, 1999
A. Manoharan, Rosalie Gemmell, Timothy Brighton, Scott Dunkley, Karen Dunn Lopez, P. Kyle   +5 more
openalex   +1 more source

Liver Stiffness Rises Early in MASLD and Drives Inflammation, Lipid Dysmetabolism, and Fibrosis via Piezo1–YAP Mechanotransduction

Advanced Science, EarlyView.
Progressive stiffening of the hepatic extracellular matrix and free fatty acid overload activate the mechanosensor Piezo1 in steatotic hepatocytes, inducing calcium influx and nuclear translocation of Yes‐associated protein. YAP‐dependent nuclear signaling further drives inflammatory and fibrotic gene programs, lipid metabolic reprogramming, and ...
Juan Ma, Ning Xie, Ziwei Wang, Xiru Liang, Yulong Han, Qiang Zhao, Ming Wang, Hongwei Lu, Wanyi Kou, William Alazawi, Jinhai Wang, Lu Li, Ning Liu, Na Liu, Haitao Shi, Feng Xu   +15 more
wiley   +1 more source

Molecular diagnosis of inherited platelet disorders: a tale of two realities - advanced vs. resource-limited setting. [PDF]

Thromb J
Safdari SM, Jozdani S, Mottaghizadeh-Jazi M, Shayanmanesh M, Khanahmad A, Bakhtiyaridovvombaygi M, Rezazadeh A, Tabibian S.   +7 more
europepmc   +1 more source

Blood platelet disorders.Advances in diagnosis and treatment.1.Basic matters for diagnosis.4.Case in which a blood platelet disorder is viewed.

, 1993
渡辺 清明
openalex   +2 more sources

Biomimetic Membrane Interface Technologies for Detection and Isolation of CTCs and EVs: Advances and Opportunities in Liquid Biopsy

Advanced Science, EarlyView.
Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu, Jie Yu, Jingxue Li, Yixue Chen, Mengle Peng, Yifan Xu, Yongjun Wu, Lihua Ding, Sitian He   +8 more
wiley   +1 more source

Platelet-to-lymphocyte ratio as a potential marker for routine management of renal anemia in maintenance hemodialysis patients: A single-center observational study. [PDF]

Medicine (Baltimore)
Yang T, Zhang J, Cao T, Liu C.
europepmc   +1 more source