Results 51 to 60 of about 629,937 (377)

Diagnosis of hereditary platelet disorders in the era of next‐generation sequencing: “primum non nocere”

Journal of Thrombosis and Haemostasis, 2019
Inherited platelet disorders can affect “only platelets”, occur as a “syndromic phenotype” or be associated with “increased risk of hematological malignancies”. Genetic testing is attractive for diagnosis of inherited platelet disorders.
A. Greinacher, Julia J. M. Eekels
semanticscholar   +1 more source

Congenital platelet disorders and health status–related quality of life

Research and Practice in Thrombosis and Haemostasis, 2019
Patients with congenital blood platelet disorders (CPDs) demonstrate a predominantly mucocutaneous bleeding tendency. Repeated bleeds throughout life can have a significant impact on health status–related quality of life (HR‐QoL), but few studies have ...
Maaike W Blaauwgeers, M. Kruip, E. Beckers, M. Coppens, J. Eikenboom, K. V. van Galen, R. Tamminga, R. Urbanus, R. Schutgens   +8 more
semanticscholar   +1 more source

Inhibitors in Patients with Congenital Bleeding Disorders Other Than Hemophilia [PDF]

, 2017
The most worrying complication of replacement therapy for severe hemophilia A and B is currently the occurrence of inhibitory alloantibodies against infused factor VIII and factor IX, respectively.
Franchini, Massimo, Liumbruno, Giancarlo Maria, Marano, Giuseppe, Mengoli, Carlo, Piccinini, Vanessa, Pupella, Simonetta, Vaglio, Stefania   +6 more
core   +1 more source

Quality control improvement at Jana DCS Sdn. Bhd. [PDF]

, 2020
Jana DCS Sdn. Bhd. is one of the companies that run the service of air conditioning system supply in Nusajaya, Johor, Malaysia. Quality improvement is one of the most important part when talking about a company, mostly companies that operate in service ...
Abd Wahab, Muhammad Badrul Amin, Mahmood, Salwa, Mohamad Rus, Mohamad Arif, Mustar, Muhamad Radzi, Raja Mamat, Tengku Nur Azila   +4 more
core  

Exogenous application of platelet-leukocyte gel during open subacromial decompression contributes to improved patient outcome [PDF]

, 2007
Background: Platelet-leukocyte gel (PLG) is being used during various surgical procedures in an attempt to enhance the healing process. We studied the effects of PLG on postoperative recovery of patients undergoing open subacromial decompression (OSD ...
Devilee, R., Everts, P., Knape, J., Mahoney, C., Oosterbos, C., Stellenboom, M., Van Erp, A., Van Zundert, Adrien   +7 more
core   +2 more sources

Human phenotype ontology annotation and cluster analysis to unravel genetic defects in 707 cases with unexplained bleeding and platelet disorders

Genome Medicine, 2015
BackgroundHeritable bleeding and platelet disorders (BPD) are heterogeneous and frequently have an unknown genetic basis. The BRIDGE-BPD study aims to discover new causal genes for BPD by high throughput sequencing using cluster analyses based on ...
S. Westbury, E. Turro, D. Greene, C. Lentaigne, A. Kelly, T. Bariana, Ilenia Simeoni, X. Pillois, A. Attwood, S. Austin, Sjoert B. G. Jansen, T. Bakchoul, Abigail Crisp-Hihn, W. Erber, R. Favier, Nicola S. Foad, M. Gattens, J. Jolley, R. Liesner, Stuart Meacham, C. Millar, A. Nurden, K. Peerlinck, D. Perry, Pawan Poudel, Sol Schulman, H. Schulze, J. Stephens, B. Furie, P. Robinson, C. van Geet, A. Rendon, K. Gomez, M. Laffan, Michele P. Lambert, P. Nurden, W. Ouwehand, S. Richardson, A. Mumford, K. Freson   +39 more
semanticscholar   +1 more source

Use of microfluidics to assess the platelet-based control of coagulation

Platelets, 2017
This paper provides an overview of the various types of microfluidic devices that are employed to study the complex processes of platelet activation and blood coagulation in whole blood under flow conditions. We elaborate on how these devices are used to
Magdolna Nagy, Johan W. M. Heemskerk, Frauke Swieringa   +2 more
doaj   +1 more source

Standardization and reference ranges for whole blood platelet function measurements using a flow cytometric platelet activation test

PLoS ONE, 2018
Introduction Platelet function testing with flow cytometry has additional value to existing platelet function testing for diagnosing bleeding disorders, monitoring anti-platelet therapy, transfusion medicine and prediction of thrombosis.
D. Huskens, Yaqiu Sang, Joke Konings, Lisa N van der Vorm, B. de Laat, H. Kelchtermans, M. Roest   +6 more
semanticscholar   +1 more source

Prevalence of platelet reactive antibodies in patient′s refractory to platelet transfusions

Asian Journal of Transfusion Science, 2014
Introduction & Aims: Though platelet transfusions have greatly reduced the incidence of major haemorrhagic complications associated with the management of haematological and oncological disorders, refractoriness to infused platelets becomes a major ...
Nitin Agarwal, Kabita Chatterjee, Alok Sen, Praveen Kumar   +3 more
doaj   +1 more source

Evaluating hemostatic thresholds for neuraxial anesthesia in adults with hemorrhagic disorders and tendencies: A scoping review

Research and Practice in Thrombosis and Haemostasis, 2021
Neuraxial anesthesia can be complicated by spinal or epidural hematoma and may result in permanent neurologic injury. There is a paucity of literature characterizing this serious complication in patients with congenital and acquired hemorrhagic disorders
Wynn Peterson, Brandon Tse, Rachel Martin, Michael Fralick, Michelle Sholzberg   +4 more
doaj   +1 more source