Results 91 to 100 of about 5,011,779 (389)

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Cyclic Helix B Peptide in Preservation Solution and Autologous Blood Perfusate Ameliorates Ischemia-Reperfusion Injury in Isolated Porcine Kidneys

Transplantation Direct, 2015
Background There is a critical need to better preserve isolated organs before transplantation. We developed a novel nonerythropoiesis cyclic helix B peptide (CHBP) derived from erythropoietin, which has potent tissue protection and prolonged serum ...
Cheng Yang, S. Hosgood, P. Meeta, Y. Long, T. Zhu, M. Nicholson, Bin Yang   +6 more
semanticscholar   +1 more source

Intestinal neuromuscular function after preservation and transplantation [PDF]

, 1996
While it is well known that prolonged preservation of the intestinal graft causes severe mucosal damage after transplantation, little is known about the effect on neuromuscular function.
Hamada, N, Hutson, WR, Ikoma, A, Nakada, K, Starzl, TE, Suzuki, T, Todo, S, Zhu, Y   +7 more
core   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Assessing the Impact of Blood Pressure on Cardiac Function Using Interpretable Biomarkers and Variational Autoencoders [PDF]

, 2019
Maintaining good cardiac function for as long as possible is a major concern for healthcare systems worldwide and there is much interest in learning more about the impact of different risk factors on cardiac health. The aim of this study is to analyze the impact of systolic blood pressure (SBP) on cardiac function while preserving the interpretability ...
arxiv   +1 more source

Graft preservation with heparinized blood/saline solution induces severe graft dysfunction.

Interactive Cardiovascular and Thoracic Surgery, 2015
OBJECTIVES Vascular grafts are often stored in cold physiological saline/heparinized blood preservation solution. Until now, only in vitro studies investigated the effect of the aforementioned preservation solutions on endothelial function. The main goal
G. Veres, P. Hegedűs, E. Barnucz, Raphael Zöller, S. Klein, T. Radovits, S. Korkmaz, M. Karck, G. Szabó   +8 more
semanticscholar   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

Estudo da preservação do pulmão de cão mantido em autoperfusão Lung preservation in dogs kept under autoperfusion

Brazilian Journal of Cardiovascular Surgery, 1991
Foram estudados 14 blocos coração-pulmão (BCP), nos quais os pulmões foram mantidos em sistema de autoperfusão em período de duas até oito horas. Realizaram-se biópsias pulmonares a cada duas horas.
Ronaldo D Fontes, Roberto Falzoni, Ricardo Magaldi, Taro Kosai, Mário Seguchi, Marcelo Tarigoe, Noedir A.G Stolf, Antônio F Ramires, Adib D Jatene   +8 more
doaj  

Comparison of robotic assisted and laparoscopic radical resection for rectal cancer with or without left colic artery preservation

Scientific Reports
The preservation of the left colic artery (LCA) during rectal cancer resection remains a topic of controversy, and there is a notable absence of robust evidence regarding the outcomes associated with LCA preservation.
Mingrui Jiang, Jin Ji, Qi Zhang, Longhe Sun, Yong Ji, Jie Wang, Muhammad Ali, Qiannan Sun, Yong Wang, Bin Liu, Jun Ren, Liuhua Wang, Wei Wang, Dong Tang, Daorong Wang   +14 more
doaj   +1 more source

PPG2ABP: Translating Photoplethysmogram (PPG) Signals to Arterial Blood Pressure (ABP) Waveforms using Fully Convolutional Neural Networks [PDF]

arXiv, 2020
Cardiovascular diseases are one of the most severe causes of mortality, taking a heavy toll of lives annually throughout the world. The continuous monitoring of blood pressure seems to be the most viable option, but this demands an invasive process, bringing about several layers of complexities.
arxiv