Results 51 to 60 of about 3,006,264 (294)

Subnormothermic Perfusion with H₂S Donor AP39 Improves DCD Porcine Renal Graft Outcomes in an Ex Vivo Model of Kidney Preservation and Reperfusion

Biomolecules, 2021
Cold preservation is the standard of care for renal grafts. However, research on alternatives like perfusion at higher temperatures and supplementing preservation solutions with hydrogen sulfide (H2S) has gained momentum.
Smriti Juriasingani, Aushanth Ruthirakanthan, Mahms Richard-Mohamed, Masoud Akbari, Shahid Aquil, Sanjay Patel, Rafid Al-Ogaili, Matthew Whiteman, Patrick Luke, Alp Sener   +9 more
doaj   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Invest to Save: Report and Recommendations of the NSF-DELOS Working Group on Digital Archiving and Preservation [PDF]

, 2003
Digital archiving and preservation are important areas for research and development, but there is no agreed upon set of priorities or coherent plan for research in this area.
Hedstrom, M., Ashley, K., Duff, W., Gladney, H., Ross, S., Moore, R., Neuhold, E., Christensen-Dalsgaard, B., Huc, C., Kenney, A. R.   +9 more
core  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Preservation of blood form elements under the protection of combined cryopreservative during low-temperature freezing

Siberian Journal of Life Sciences and Agriculture
Background. Cryopreservation has found wide application for various purposes but the disadvantages of existing cryoprotective agents lead to the loss of cell functionality, which can negatively affect the further use of preserved material.
Aleksandr A. Vlasov, Svetlana F. Andrusenko, Evgeniya V. Denisova, Aishat B. Elkanova, Dmitry A. Bogoslovsky, Inna V. Sivun   +5 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

SEPARATION OF LEUCOCYTES FROM PERIPHERAL BLOOD OF DOGS [PDF]

Assiut Veterinary Medical Journal, 1985
In the present study, an efficient method for separation, concentration and preservation of dog leucocytes from the peripheral blood were described. Statistical methods were carried out to postulate the chan ges in each test done.
A.Z. MAHMOUD, M.K. IBRAHIM, A.H. BAYOUMI
doaj   +1 more source