Results 51 to 60 of about 3,193,301 (293)

Preservation of blood form elements under the protection of combined cryopreservative during low-temperature freezing

open access: yesSiberian Journal of Life Sciences and Agriculture
Background. Cryopreservation has found wide application for various purposes but the disadvantages of existing cryoprotective agents lead to the loss of cell functionality, which can negatively affect the further use of preserved material.
Aleksandr A. Vlasov   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

SEPARATION OF LEUCOCYTES FROM PERIPHERAL BLOOD OF DOGS [PDF]

open access: yesAssiut Veterinary Medical Journal, 1985
In the present study, an efficient method for separation, concentration and preservation of dog leucocytes from the peripheral blood were described. Statistical methods were carried out to postulate the chan ges in each test done.
A.Z. MAHMOUD, M.K. IBRAHIM, A.H. BAYOUMI
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Improved maternal outcome in placenta accreta spectrum disorders: a single-institute observational cohort study

open access: yesBMC Pregnancy and Childbirth
Background To describe the evolution and outcomes of protocol-orientated multidisciplinary quality improvement for clinically confirmed placenta accreta spectrum (PAS) disorders mainly receiving uterine preservation.
Hang Zhou   +7 more
doaj   +1 more source

A novel technique for isolating DNA from Tempus™ blood RNA tubes after RNA isolation

open access: yesBMC Research Notes, 2018
Objective We use Tempus blood RNA tubes (Applied Biosystems) during health assessments of American moose (Alces alces spp.) as a minimally invasive means to obtain RNA.
Jason A. Ferrante   +3 more
doaj   +1 more source

Preservation Working Group Survey 2013-5-04

open access: yes, 2013
This document presents results from the International Internet Preservation Consortium Preservation Working Group Survey on web archiving and digital preservation ...
International Internet Preservation Consortium. Preservation Working Group
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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