Results 71 to 80 of about 13,953,309 (254)
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith +12 morewiley +1 more sourceDelivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
FEBS Open Bio, EarlyView.Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow +12 morewiley +1 more sourceIn silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic +6 morewiley +1 more sourceGenetic variants in novel pathways influence blood pressure and cardiovascular disease risk [PDF]
, 2011 Blood pressure is a heritable trait1 influenced by several biological pathways and responsive to environmental stimuli. Over one billion people worldwide have hypertension ($140mmHg systolic blood pressure or$90mmHg diastolic blood pressure)2. Even small Harst, P. (Pim) van der, Lawrence, Robert W, Sinning, Christoph, Wichmann HE, Preuss, M., Ridker, P.M., Wilensky R, Launer, L, Assimes, Themistocles L., Go, Alan, Heid, I. M., Ingelsson, E., Elosua, R., Fava, C. (Cristiano), Staessen, J.A. (Jan), Kim, HL, Boerwinkle, E., Dong, Y., Prabhakaran, D, van der Schouw, Y.T., Hicks, Andrew A, Ongen, H. (Halit), Palmer, L.J., Langefeld, C.D. (Carl), Hengstenberg, Christian, Wichmann, H. Erich, Kangas, Antti J., Glazer, NL, Shin Cho, Y. (Yoon), Smith, Nicholas, Peters, Annette, Tayo, B. (Bamidele), Young, J. Hunter, Smith, AV, Day, I.N.M., Lathrop, Mark, Steinle, NI, Stančáková, A, Curhan, G. C., Dong, YB, Preuss M, Cooper, Richard S, Glazer, N., Kuznetsova, T, Barroso, Inês, Ong, R.T., Lawrence, Robert W., O´Connell, J.R., Forrester, T, Corsi, A.M. (Anna Maria), Vinay, D G, Chambers, John C, Tomaszewski, M, Palmer, Lyle J., O'Donnell, CJ, Frayling, Timothy M., Nilsson, Peter M., Wichmann, H.E. (Heinz Erich), Floege, J., Seielstad, M, Hwang, S. J., Roberts, Robert, Igl, W., Harris, T.B. (Tamara), Knowles, J., Ongen, Halit, Voelker, Uwe, Quertermous, T., Seielstad, Mark, Heckbert, Susan R., Lee, NR, Miki, T., Johnson, A.D. (Andrew), Li, Mingyao, Nilsson, P. (Peter), Munroe, PB, Kong, A., Ong, RT, Schillert, A., Perret, Claire, Ludwig, Barbara, Thorgeirsson, G., Milaneschi, Y. (Yuri), Smith, GD, Rivadeneira, F, Turner, S. T., Chang, Yen-Pei C, Bilo, H. J., Sidney, Steven, Fava, Cristiano,, Salako, T., Iwai, N., Lackner, K., Strachan, David P., Schreiber, S., Morris, R.W. (Richard), Ohkubo, T, Johnson, T, Ong, RTH, Nelson C, Sinning C, Bolton, J.A.H., Chen L, Wu, Fenny, Rudan, I. (Igor), König, I. R., Winkelmann, B.R., Orru, Marco, Järvelin, M.-R., Najjar, S., Nicaud, Viviane, O’Donnell, Christopher J., Tripathy, Vikal, Uitterlinden, Andre G, Braund, Peter S., van Gilst, WH, Smith, A.V. (Albert Vernon), Quertermous T, Völker, U. (Uwe), Fortmann, Stephen, Knouff, C.W., Zillikens, M. C., Sternberg, M. J., Rice, K.M., Zhang, W., Illig T, Levy, D. (Daniel), Taylor, K.D., Gyllensten, Ulf B, Andersen, K., Mani, K Radha, Milaneschi, Y, Raitakari, Olli T., Vitart, Veronique, Völzke, H. (Henry), Emilsson, V., Hercberg, S., Iribarren, Carlos, Nguyen, Khanh-Dung Hoang, Waterworth, Dawn M., Lucas, Gavin, Cupples, L.A., Kähönen, M., Loley, Christina, Cavalieri, M., Dominiczak, Anna F, Wright, A.F., van der Schouw, YT, Gao, X., Hadley, D., Sijbrands, Eric J.G., Burtt N, Talmud, P.J., Hakonarson, H.H., et al, Kangas, AJ, Gale, D. P., Graessler, J, Wareham, N.J., Scharnagl H, Li, Y., de Faire, Ulf, Longstreth Jr., W.T., Wild, S.H. (Sarah), Heath, S., Weder, A.B. (Alan), Erdmann, Jeanette, Gabriel SB, Zhu, H. (Haidong), Artigas, M.S., Dehghan A, Stancáková, A. (Alena), Illig, T., Soininen, P. (Pasi), Galan, P., Li, YL, Yang, Q., van Gilst, Wiek H, Zhang, WH, Swift, A.J. (Amy), Vineis, P., Hicks, Andrew A., Brand, Stefan Martin, Tai, E Shyong, Jackson, A.U., Knouff, Christopher W., Hoffmann M, Wilson, James F, Whincup, P.H., Wong, TY (Tien Yin), Longstreth Jr, W. T., Org, E, Bornstein, SR, KidneyGen Consortium, Völzke, H, Parker, AN, Wagenknecht, Lynne E., Wass, M. N., Schillert A, Witteman, Jacqueline C.M., Kroemer, H. K., Wu, Y, Hofman A, Guarrera, S, Köttgen, Anna, Chen, I.Y., Dobnig H, Erdmann, J, Adeyemo, A. (Adebowale), Nelson, C., Wright, AF, Boban, M., Larson, Martin G., Najjar, Samer S., Meschia, James F, Farrall, M. (Martin), Hercberg, Serge, Palmer, LJ, Kooner, J.S. (Jaspal), Parker, A. N., Beckmann, Jacques S, Hicks, A.A., Sijbrands, EJ, ICBP Consortium (Meitinger, T. ; Wichmann, H.-E. ; Gieger, C.), Hua Zhao, Jing, Brand, Eva, Waterworth, D., Melander, O, Qu, Liming, Polasek, Ozren, Miki, T, Grässler, J., Medack A, Shriner, D, Chang, Yen-Pei C., Snieder, H. (Harold), Uiterwaal, C.S.P.M., Salomaa, V. (Veikko), van Duijn, Cornelia M., Sehmi, J.S., Zerres, K., Mosley, Thomas H., Kao, WHL, Psaty, B. M., Groop, L. (Leif), Lakatta, Edward G., Ehret, Georg B, Heckbert, S. R., Renner W, Sõber, S. (Siim), Terzic, J. (Janos), Bakker, S.J.L. (Stephan), Jackson, Anne U, Newton-Cheh, C, Ikram, Arfan, Snieder, Harold, Grobbee, D.E. (Diederick), Marciante, Kristin, Struchalin, M., Gabriel, Stacey B., Fowkes, F. Gerald R., Palmas, W, Collins, FS, Lumley, Thomas, Fowkes, F.G.R., Kim, Hyung Lae, Janipalli, C.S., Hernandez, Dena, Zhao, JH, Kumar, M. V. Kranthi, Kuusisto, J. (Johanna), Laakso, M. (Markku), Shrine, N.R., Kivimaki, M., Chen, M.H., Longstreth, W. T., Jr., Chang, Y.-P.C. (Yen-Pei), Langefeld, Carl D., Pramstaller, PP, Hoang Nguyen, KD, Uiterwaal, CSPM, Greiser, K. H., Vollenweider, P, Smith, A., Najjar, S.S. (Samer), Rotimi, C, Halperin, Eran, Coresh, J., Ala-Korpela, M. (Mika), Barroso, I.E. (Inês), Zhu, Haidong, Elliott, P., Fuchsberger, C., Prabhakaran, Dorairaj, Palmas, W., Hilton, Gina, Demissie, Serkalem, Whincup, Peter H., Tanaka, T, Humphries, S.E. (Steve), Cupples LA, Steinle, Nanette I., Hwang, S-J, Psaty, Bruce M., Salako, Tunde, Onland-Moret, N.C. (Charlotte), Jarinova, O., Mägi, R., Vinay, D. G., Beilby, John P, Smith, N.L., Elosua, Roberto, Demirkan, A, Tuomilehto, J., Zhai, G. (Guangju), Swift, Amy J, Galan, P, Köttgen, A., Morrison, Alanna C, Hoffmann, Michael M., Arfan Ikram, M., Uiterwaal, CS, Walker, M.C., Gaunt, Tom R., Deloukas, P, Launer, L. J., Ehret, G.B., Prabhakaran, D., Lakatta, EG, Krämer, B. K., Holm H, Bis, J.C. (Joshua), Franke, A., Cooper, Jackie A., Chasman, D.I. (Daniel), Lieb, W., Mohlke, K.L., Campbell, Harry, Teumer, A. (Alexander), Garcia, Melissa E, Voight, Benjamin F, Lyytikäinen, L.-P., Pichard AD, Scott, J., Ellinghaus, D., Mattace-Raso, Francesco U.S., McKenzie, C.A., Lyytikainen, L-P, Bochud, M., Hlatky M, Bergmann, S, Plump, A., Tang, Hua, Lawrence, RW, Medack, A., Parsa, A., Khaw, KT, Hartikainen, AL, Schnabel R, Talmud, Philippa J., Hoffman Bolton, Judith A., Grosshennig A, Heckbert, Susan, Yajnik, C.S., Charchar, Fadi J., Heckbert, S.R. (Susan), Satler, Lowell, Rotter JI, Hernandez, D.G. (Dena), Erdmann, J. (Jeanette), Chasman, DI, Adeyemo, A, Zhu, H, Smith, G.D., Denniff, M. (Matthew), Absher D, Matthai, W., Doering, Angela, Young, J Hunter, Rao, Dabeeru C., Thompson, J.R., Zelenika, D, Mattace-Raso, Francesco U S, Alexander, Myriam, Zhu, X, Lathrop, G.M. (Mark), Li, M., Langefeld, C.D., Bots, ML (Michiel), Kangas, A.J. (Antti), Bis, J.C., Wilson, J.F., Doumatey, Ayo P., Samani, N.J., Meisinger C, Okamura, Tomonori, Kent, K.M., Kathiresan, S, Rader, Daniel J., Schwartz, S.M. (Stephen), Raitakari, O., Friedrich, N., International Consortium for Blood Pressure Genome-Wide Association Studies, Platou, C. (Carl), Connell, J. M., Samani NJ, Beilby, JP, Palmer, ND, Wong, Tien Y, Knowles, Joshua, Howard, P, Soranzo, N., Adair, LS, Schmidt, H., Epstein, S., Waeber, G., Pouta, A., Rotter, J. I., Perola, M. (Markus), Wichmann, HE, Day, Ian N.M., Preuss, Michael, Brand, E (Eddy), Isaacs, A., Kardia, Sharon L. R., Homan van der Heide, J. J., Chang, Y-PC, Arnett, D. K., Hwang, S.J., Brand, E, Burton, P.R. (Paul), Wilson, James F; id_orcid, Corsi, Anna Maria, O'Reilly, P.F., Bergmann, S., Voelker, U, Völker, U., Rettig, R. (Rainer), Kuh, D, Bickel, Christoph, Frayling, Timothy M, Farrall, M., Teumer, Alexander, Umemura, S., Matullo, G., Dominiczak, Anna F., Demirkan, A. (Ayşe), Wells, G.A., Ehret, Georg B., Laan, M, Emilsson, Valur, Zelenika, D. (Diana), Aulchenko, Yurii S., Cupples, L. Adrienne, Bakker, Stephan J.L., Peden, John F., O’Reilly, Paul F., Lakatta, Edward G, Vasan, RS, Beckmann, J.S. (Jacques), Lawlor, D. A., Loehr, Laura R., Prokopenko, I, Kuznetsova, T. (Tatiana), Chambers, J.C., Khaw, Kay-Tee, Viigimaa, M., Day, I.N., Raffel, Leslie J, Sijbrands, E.J.G. (Eric), Taylor, A., Schlieper, G., van der Schouw, Yvonne T., Ganesh, Santhi K, Samani, Nilesh J, Peltonen, L. (Leena Johanna), Kardia, S.L., Tomaschitz A, Rodeheffer, R. J., McArdle, W.L., Melander, O., Parsa, A. (Afshin), Cooper, J.A., Wong, T.Y., Zitting, P. (Paavo), Sidney, S., Fox, E.R. (Ervin), Gretarsdottir, Solveig, Khanh-Dung Hoang, Nguyen, Hayward, Caroline, Hofman, A. (Albert), Nahrstedt, J., Erdmann J, Ohkubo, T., Voight, B.F., Igl, Wilmar, Steinle, N.I. (Nanette), Wild, S. H., Lackner, K. J., CARDIoGRAM Consortium, Kroemer, H.K., Ala-Korpela, Mika, Caulfield, MJ, Haritunians, T., Coresh, J, Fowkes, FGR, Rasheed, A. (Asif), Balmforth AJ, Schmidt, R., Winkler K, Kooner, JS, McKenzie, Colin A., Hicks, AA, Kuusisto, Johanna, Aspelund, T, Chang, Y.-P.C., Mattace-Raso, FU, Adeyemo, A., Morris, Richard W, Lakatta, E.G., International Consortium for Blood Pressure Genome-Wide Association Studies,, Dreisbach, A.W., Oostra, B.A., Emilsson, V, Watkins, Hugh, Freyer, J., Shi, G. (Gang), Kulkarni, SR, Thelle, Dag S, Morken, Mario A, Fowkes, F.G.R. (Gerald), Jafar, T.H., Ramachandran, Vasan, O'Reilly, P.F. (Paul), Renner, Wilfried, Viigimaa, Margus, Saleheen, Danish, Spector, T.D., Sijbrands, E.J., Loos, R.J.F., Kinra, S, Howard, P., Sjögren, Marketa,, Scott, LJ, Gulde, Stephanie, Kathiresan, Sekar, Rice, Kenneth M, Larson, Martin G, Wilson, JF, Gyllensten, U.B., Han, B.-G., Kardia, S.L. (Sharon), Holm, H., Abecasis, G. R., Lohman, Kurt K., Aulchenko, Yurii, Rupprecht HJ, Arora, P., Bots, Michiel L., Münzel T, Absher, D., Alexander, M. (Myriam), Hwang, Shih Jen, Kulkarni, S.R., Aulchenko, Yuriy, Gaunt, Tom R, Wilson, J.F. (James), Wong, TY, Sõber, Siim, Meitinger, T. (Thomas), Wain, Louise V, Bickel C, Grosshennig, A., Cooper, M.N. (Matthew), Zukowska-Szczechowska, E., Hopewell, J.C., Barbalic M, McPherson, R., Ikram, M.A. (Arfan), Palmen, J., Barroso, Ine S., Lee, JY, Wagenknecht, L.E. (Lynne), Lackner, Karl, Hlatky, M., Vartiainen, E., Uda, M., Danesh, J, Weder, Alan B., Rivadeneira Ramirez, F. (Fernando), Connell, J.M., Linsel-Nitschke, P., Wong, Tien Y., Böhm BO, Harris, Tamara B, Watzinger, N., Morrison, A.C. (Alanna), Kathiresan, S., Okamura, T. (Tomonori), Ong, Rick Twee Hee, Kettunen, Johannes, Bickel, C., Campbell, H. (Harry), Caulfield, M. (Mark), Groop, L, Boehnke, M, Walker M, Wichmann, H.-E., Kathiresan S, Folsom, A., Willenborg, C., Shi, Gang, Knowles J, Chen, Ming Huei, Zhu, H., van Duijn, C. M., Peltonen, L, Humphries, S.E., Kita, Y, Sidney S, Kao, W.H.L., Blankenberg, Stefan, Levy D, Cooper, Matthew N, Zhu, HD, Melander, Olle,, Peden, J. (John), Kumari, M. (Meena), Terzic, J., Whincup, PH, Swift, A.J., Ueshima, H. (Hirotsugu), Thorgeirsson, Gudmundur, Tayo, B., Sehmi, J. S., Demirkan, A., Bochud, Murielle, Doumatey, A, Nalls, Michael A., Humphries, Steve E, Parker, A.N. (Alex), Ebrahim, S., Hveem, K., Longstreth, W T, Kong, Augustine, Taylor KD, Mooser, Vincent, Uitterlinden, AG, Heckbert, Susan R, Orru, M., Gieger, C, Kumar, MV, Pichard, A.D., Harris, Tamara, Laaksonen, R., Levy, Daniel, Wiggins, K.L. (Kerri), Khaw, K-T. (Kay-Tee), Wichmann, H-Erich, Tobin, M.D. (Martin), Burnett, Mary Susan, Cooper, RS, Goel, Anuj, Wong, A., Dockrell, M., Watkins, H., Aspelund, T. (Thor), Thelle, Dag S., Vineis, Paolo, Schlessinger, D., Roberts R, Narisu, N., Lindsay, J.M., Platou, C.G.P., Chang, YPC, Andersen K, Ueshima, Hirotsugu, van Duijn, CM, Lee, J.Y., Nauck, M., Lawrence, R.W. (Robert), Bakker, Stephan J. L.; id_orcid, Langefeld, CD, Bots, Michiel L, Campbell, Harry; id_orcid, Longstreth jr., W. T., Wiggins, K.L., Kuznetsova, Tatiana, Meschia, JF, Ferrucci, L. (Luigi), Chasman, Daniel I, Kumar, M V Kranthi, Kolcic, I., Sõber, S, Singleton, Andrew, Ridker, P. M., Johnson, T., van Duijn, C., Salomaa, V, Sjögren, M, Kinra, S. (Sanjay), Hveem, K. (Kristian), Lumley T, Shuldiner, A.R., McKenzie, CA, Han, BG, Rudock, M.E., Paré, G., Soranzo, N. (Nicole), Seshadri, S., Platou, C.G., Hilton, G., Brown, MJ, Lagou, V., Halperin, E., Vineis, P. (Paolo), Wiggins, Kerri L, Province, M., Uda, Manuela, Ricceri, F. (Fulvio), Prokopenko, Inga, Marciante, K., Parker, Alex N., Harris T, O'Donnell CJ, Ikram, M Arfan, Felix, J. F., Snieder, H, Bergmann, Sven, Lawlor, Debbie A., Launer, Lenore J., Fox, C. S., Bergmann, S.M. (Sven), Wichmann, H. E., Loos, R.J.F. (Ruth), Wareham, N.J. (Nick), Adair, L.S., Hingorani, Aroon D., Rotimi, C. (Charles), Scuteri, A., König IR, Luan, Jian’an, Kleber, Marcus, Dreisbach, Albert W, Ueshima, H., Raffel, L.J. (Leslie), Rotter, Jerome I, Marmot, MG, Badola, S., Kuh, D., Hengstenberg C, Cambien, F., Dikkeschei, L. D., Goel, A., Bornstein, S.R. (Stefan), Thompson, John R., Walker, Max C., Risch N, Kim, H-L, Stojakovic, Tatjana, Hunt, Steven C, Terzic, Janos, Erdmann, J., Arora, Pankaj, Aulchenko, Y. S., Laitinen, J, Wagenknecht, Lynne E, Janipalli, CS, Chambers, J. C., Sjögren, Marketa, Fowkes, F.G., Raffel, L.J., Absher, Devin, van der Harst, Pim, Adeyemo, Adebowale, Perucha, E., Lucas, G. (Gavin), Palmer, Nicholette D., Sun, Yan V, Corsi, A.M., Schwarz, P.E., Tobin, Martin D, Jarinova O, Sun, Yan V., Artigas, Maria Soler, Nguyen, KD, Homuth, G., Maxwell, P. H., Dobnig, H., Onland-Moret, Charlotte N, Gretarsdottir, S., Jafar, T.H. (Tazeen), Uitterlinden, A. G., Sharma, P. (Pankaj), Mooser, V. (Vincent), Shaw-Hawkins, S. (Sue), Loley C, Koettgen, A, Guarrera, Simonetta, Wain, L.V. (Louise), Beckmann, J.S., Zgaga, L., Bolton, Judith A Hoffman, Stenvinkel, P., Kinra, Sanjay, Chambers, John C., Dahgam, S, Polasek, O., Lohman, Kurt K, Würtz, P., Kullo, I., Uitterlinden, A., Kumar, MV Kranthi, Brand, S-M, Kita, Yoshikuni, Morrison, Alanna, Collins, Francis S., Schunkert H, Iwai, N, Nalls, Michael A, Harris, TB, Wu, Y., Casas, Juan P., Deloukas, Panos, Pilz S, Ohkubo, Takayoshi, Harris, T., Shrine, Nick RG, Wareham, Nicholas J., Dahgam, S. (Santosh), O'Connell, J.R., Sim, X. (Xueling), Saleheen, D., Stewart, A.F., Arking, Dan E., Laitinen, Jaana, Brand, S.-M., Bakker, S. J., Abecasis, GR, Oostra, B.A. (Ben), Wang, TJ, Maria Corsi, Anna, Go, Min Jin, Kardia, Sharon L., Burtt, Noel, Ludwig, B, Zhao, J.H., Cooper, Jackie A, Vitart, V, Larson, M.G., Shaw-Hawkins, S, Fortmann S, Hayward, C, Waterworth DM, Mattace-Raso, F.U., Chen IY, Wang, X., Seelen, M. A., Gyllensten, U. (Ulf), Strachan, DP, Vasan, R.S., Böhm, Bernhard O., Lakatta, E. (Edward), Glazer, N.L., Kettunen, J, Cooper, R.S., Bornstein, Stefan R., Spector, TD, Vineis, P, Taylor, A. (Andrew), Tang, H., Wang, W., Tukiainen, Taru, Sehmi, Joban S., Milaneschi, Y., Wichmann, H. -Erich, Ferrucci, L., Nelson, Chris, Connell, JM, Hartikainen, A.L., Oostra, B. A., Hveem, Kristian, Bis, J. C., Forrester, T. (Terrence), Dahgam, Santosh, Munzel, T. F., Raffel, Leslie J., Denniff, Matthew, Lee, N.R. (Nanette), Isaacs, A, Zhu, XF, Tabara, Y, Peden, JF, Uda, M. (Manuela), Lehtimäki, T, Sim, Xueling, Strachan, David P, Shi, G., Mitchell, G. F., Tiret L, Guarrera, S., Abecasis, G.R. (Gonçalo), Winkler, Karl, Vasan, R. S., Spector, T. D., Radha Mani, K., Altshuler D, Samani, Nilesh J., Platou, CGP, Campbell, H, Bakker, Stephan J. L., Marciante K, Hofman, Bert, Wright, A. F., Nguyen, K.D., Gulcher, Jeffrey R., Burton, Paul R., Hunt, SC, Hercberg, S. (Serge), Watkins, H, Chang, YP, Bolton, Judith A. Hoffman, Ferrucci, Luigi, Zhu, X., Kardia, Sharon L, Kumar, M.V., Pichard, Augusto D., Spector, Tim D., Olden, M, Sijbrands, Eric J G, Olden, M., Gansevoort, R. T., Snieder, H., Wang, Xiaoling, Nitsch, D., Nicaud V, Arking, D.E. (Dan), Day, IN, Wichmann, H.-Erich, Shriner, D. (Daniel), Kleber M, Gaunt, TR, Ricceri, F., Khaw, K-T, Stark, K., Charlotte Onland-Moret, N., Meneton, Pierre, Khaw, K.-T., Smith, N. L., Hakonarson, Hakon H., Würtz, Peter, Gieger, C., Umemura, S. (Satoshi), Kleber, M., Pihur, Vasyl, Verwoert, G.C. (Germaine), Ridker, Paul M, Artigas, MS, Redfield, M. M., Lyytikäinen, LP, Elliott, P. (Paul), O'Donnell, Christopher J., Jarvelin, M-R, Wild, Philipp, Rice, K.M. (Kenneth), Lawlor, DA, Altshuler, D, Clarke, Robert, Miki, Tetsuro, Seielstad, M. (Mark), Hartikainen, Anna Liisa, Chambers, JC, Coresh, J. (Josef), Waterworth, D.M., Olden, M. (Matthias), Mangino, Massimo, Hicks, A.A. (Andrew), Verwoert, Germaine, Lucas, G, Hadley, D, Wild, S.H., Miki, T. (Tetsuro), Palmas, W. (Walter), Clarke, R., Rudock, Megan E., Sim, X, Fava, Cristiano, de Andrade, M., Mosley, TH, Swaminathan, R., Werdan, K., Hamsten, A. (Anders), Zhai, Guangju, Stefansson, K., Eiriksdottir, G., Würtz, P, Tiret, L., Johnson, AD, Siscovick, D., Wilde, S. +999 morecore +2 more sourcesChronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...Anu Singh, Aroonima Misra, Sufian Zaheerwiley +1 more sourceEarly socioeconomic position and blood pressure in childhood and adulthood - The Cardiovascular Risk in Young Finns Study [PDF]
, 2005 Studies have found an association between low socioeconomic position in childhood and high adult blood pressure. It is unclear whether this association is explained by a pathway directly linking disadvantage to elevated blood pressure in childhood and ...M. Elovainio, Raitakari, OT, M. Kivimaki, Pulkki-Raback, L, Keltikangas-Jarvinen, L, L. Pulkki-Raback, L. Taittonen, O. T. Raitakari, J. S.A. Viikari, Smith, GD, Vahtera, J, Elovainio, M, Kivimaki, M, Taittonen, L, Lawlor, DA, Viikari, JSA, L. Keltikangas-Jarvinen, D. A. Lawlor, G. D. Smith, Davey Smith, G, J. Vahtera +20 morecore +1 more sourceThe Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm +4 morewiley +1 more source
