Results 91 to 100 of about 833,559 (317)

SOME FEATURES OF CURATIVE ACTION OF A MILK THISTLE OIL REALIZATION FOR LEVER TOXICAL DAMAGE WITH FORMALINE

Фармация и фармакология (Пятигорск), 2015
The article represents the results of experimental researches of metabolic disorders provoked by subacute formalin injection to rats and study of possibility for correction of received changes by the saint milk thistle oil by the changes of clinical and ...
V. V. Kozlova, D. A. Konovalov, N. N. Vdovenko-Martynova, I. V. Pshukova, A. A. Kruglaya   +4 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Differences in Disease Severity but Similar Telomere Lengths in Genetic Subgroups of Patients with Telomerase and Shelterin Mutations

, 2011
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Anna Ratcliffe, Tom J Vulliamy, Vulliamy Tom J., Kirwan, MJ, Hossain, U, Ratcliffe Anna, Vulliamy, Tom J., Baqai Charlotte, Kirwan Michael J., Baqai, Charlotte, Michael J. Kirwan, Baqai, C, Ratcliffe, A, Beswick, Richard, Marsh, Judith, Walne, Amanda, Beswick, R, Inderjeet Dokal, Dokal, Inderjeet, Walne Amanda, Kirwan, Michael J., Marsh, J, Charlotte Baqai, Judith Marsh, Marsh Judith, Tom J. Vulliamy, Beswick Richard, Dokal, I, Hossain, Upal, Vulliamy, TJ, Upal Hossain, Amanda Walne, Dokal Inderjeet, Richard Beswick, Michael J Kirwan, Ratcliffe, Anna, Hossain Upal, Walne, A   +37 more
core   +1 more source

Cortical organotypic slice cultures as a tool to analyze the neurovascular unit in hypoxia/ischemia and hypothermia-induced neuroprotection [PDF]

, 2013
Neurons and glial cells of the central nervous system (CNS) communicate and work together to function and execute an array of complex tasks. In addition to them a third cell type which also works to keep the brain alive are the cerebral endothelial cells
Chip, Sophorn
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Poly(ADP-ribose) polymerase family member 14 (PARP14) is a novel effector of the JNK2-dependent pro-survival signal in multiple myeloma [PDF]

, 2013
Copyright @ 2013 Macmillan Publishers Limited. This is the author's accepted manuscript. The final published article is available from the link below.Regulation of cell survival is a key part of the pathogenesis of multiple myeloma (MM).
Papa, S, Rahemtulla, A, Chaidos, A, Barbarulo, A, Karadimitris, A, Iansante, V, Naresh, K, Haskard, DO, Bubici, C, Franzoso, G   +9 more
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

An unusual case of multiple myeloma [PDF]

, 2013
The case concerns the unusual presentation of a non-secretory multiple myeloma with diarrhoea secondary to large bowel infiltration. In December 2009, a 74-year-old lady presented to hospital and complained of a two year history of intermittent ...
Delicata, Julian, Farrugia, Daniel
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Proteins as markers of TSE infection in sheep blood

, 2008
Transmissible spongiform encephalopathies (TSEs) are a group of fatal infectious neurodegenerative diseases affecting both humans and agricultural animals. TSE transmission via blood transfusion has been demonstrated experimentally in rodent, primate and
Martin, Joanne
core