Results 81 to 90 of about 7,188,262 (255)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Which Blood Group is More Anemic: Five Years of Retrospective Experience [PDF]

, 2023
Aim: The relationship between blood groups and diseases has been a subject of interest for many researchers. This study aims to investigate the susceptibility of each blood group to anemia based on the relationship between the erythrocyte indices and the
Akidağı, Zeynep
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Transcriptional Blood Signatures Distinguish Pulmonary Tuberculosis, Pulmonary Sarcoidosis, Pneumonias and Lung Cancers [PDF]

, 2013
Rationale New approaches to define factors underlying the immunopathogenesis of pulmonary diseases including sarcoidosis and tuberculosis are needed to develop new treatments and biomarkers. Comparing the blood transcriptional response of tuberculosis
Lipman, M, Derek Blankenship, Katalin A Wilkinson, Christine M Graham, Xu, Zhaohui, Vancheeswaran, Rama, Matthew P. R. Berry (130010), Anne O’Garra (130055), Dominique, Valeyre, Beynon, H, Banchereau, J, Rama Vancheeswaran, Guy Gorochov, Virginia Pascual, Anne O'Garra, Ling-pei Ho, Phillip Vanhems, Damien Chaussabel (26369), Pascual, V, Phillip Vanhems (441320), Xu, Z, Yvonne Kendrick (441315), Kendrick, Yvonne, Rozakeas, F, Chloe I. Bloom (130006), Lipman, Marc, Huw Beynon (441321), Vanhems, Phillip, Fotini Rozakeas, Wickremasinghe, Melissa, Christine M. Graham (130008), Miyara, M, Jacques Banchereau, Wickremasinghe, M, Marc Lipman, Matthew P. R. Berry, Diane Bouvry (441317), Yuanyuan Wang, Huw Beynon, Ferry, T, Berry, MP, Blankenship, D, Derek Blankenship (173502), Wilkinson, Robert J, Gilles Devouassoux (441316), Dominique, V, Ferry, Tristan, Paul S. Redford (441314), Robert J. Wilkinson, Berry, MPR, Matthew P R Berry, Melissa Wickremasinghe, Jacques Banchereau (4187), Wilkinson, Katalin A, Valeyre Dominique, Redford, Paul S, Zhaohui Xu, Saadatian, Mitra, Gilles Devouassoux, Berry, Matthew P R, Wang, Y, O\u27Garra, Anne, Yuanyuan Wang (20181), Rama Vancheeswaran (441322), Blankenship, Derek, Vancheeswaran, R, Katalin A. Wilkinson, Saadatian, M, Mitra Saadatian, Paul S. Redford, O'Garra, A, Chaussabel, Damien, Diane Bouvry, Devouassoux, G, Melissa Wickremasinghe (235318), Ho, LP, Robert J Wilkinson, Ho, Ling-Pei, Mitra Saadatian (441319), Guy Gorochov (89307), Wilkinson, KA, Pascual, Virginia, Rozakeas, Fotini, Katalin A. Wilkinson (130012), Robert J. Wilkinson (130050), Zhaohui Xu (130026), Damien Chaussabel, Gorochov, Guy, Graham, CM, Beynon, Huw, Valeyre, D, Tristan Ferry, Tristan Ferry (412308), Redford, PS, Bloom, Chloe I, Virginia Pascual (130037), Bouvry, D, Chaussabel, D, Chloe I. Bloom, Marc Lipman (130043), Vanhems, P, Bloom, CI, Paul S Redford, Chloe I Bloom, Ling-pei Ho (5655859), Wang, Yuanyuan, Yvonne Kendrick, Anne O’Garra, Dominique Valeyre, Gorochov, G, Kendrick, Y, Makoto Miyara, Bouvry, Diane, Banchereau, Jacques, Miyara, Makoto, Valeyre Dominique (441318), Christine M. Graham, Devouassoux, Gilles, Ho, L-P, Wilkinson, RJ, Makoto Miyara (199979), Graham, Christine M, Fotini Rozakeas (130019)   +122 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Issued by the National Blood Users Group

, 2002
Rapid and continuing loss of blood is life-threatening. Ensuring that tissue oxygenation is maintained at a level consistent with avoidance of critical ischaemic organ damage and irreversible organ failure demands speed and skill.
National Blood Users Group
core  

Genetic studies of familial myeloproliferative disorders [PDF]

, 2007
Hereditary thrombocythemia (HT) is an autosomal dominant disorder with clinical features resembling sporadic essential thrombocythemia. HT families share similar clinical symptoms caused by heterogeneous genetic alterations.
Liu, Kun
core   +1 more source

Proteins as markers of TSE infection in sheep blood

, 2008
Transmissible spongiform encephalopathies (TSEs) are a group of fatal infectious neurodegenerative diseases affecting both humans and agricultural animals. TSE transmission via blood transfusion has been demonstrated experimentally in rodent, primate and
Martin, Joanne
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

A guideline for transfusion of red blood cells in surgical patients

, 2000
Blood transfusion carries a real but unquantifiable risk of adverse outcome in surgical patients from infectious, immunological and cardiorespiratory morbid events.
National Blood Users Group
core