Results 1 to 10 of about 6,236 (223)

Epigenetic modifications as key regulators of Waldenstrom's Macroglobulinemia biology [PDF]

Journal of Hematology & Oncology, 2010
Waldenstrom's Macroglobulinemia is a low-grade B-cell lymphoma characterized by the presence of lymphoplasmacytic cells in the bone marrow and a monoclonal immunoglobulin M in the circulation.
Maiso Patricia, Liu Yang, Zhang Yong, Issa Ghayas C, Sacco Antonio, Ghobrial Irene M, Roccaro Aldo M   +6 more
doaj   +4 more sources

Zanubrutinib for high-risk Waldenström macroglobulinemia with complex karyotype and hyperleukocytosis: A case report and literature review [PDF]

SAGE Open Medical Case Reports
To report the management and outcome of an elderly, high-risk lymphoplasmacytic lymphoma/Waldenström macroglobulinemia patient presenting with severe symptomatic anemia, marked hyperleukocytosis, a complex karyotype, dual MYD88/CXCR4 mutations, and ...
Jiale Chen, Jieyi Zhou, Chengyang Xu, Bo Zheng, Jie He, Rong Li   +5 more
doaj   +2 more sources

Mixed cryoglobulinemia; a rare presentation of Waldenström macroglobulinemia [PDF]

Journal of Nephropathology, 2022
Type II mixed cryoglobulinemia is a systemic disease mediated by immune complexes. Renal involvement is present in almost one third of the cases and the membranoprolifer-ative pattern is the most common histological presentation.
Catarina Isabel Ribeiro, Clara Santos, Clara Almeida, Teresa Melo, David Tente, João Carlos Fernandes   +5 more
doaj   +1 more source

Efficacy of ibrutinib in a patient with transformed lymphoplasmacytic lymphoma and central nervous system involvement [PDF]

, 2017
Bruton's tyrosine kinase (BTK) is a non-receptor kinase that plays a crucial role in oncogenic signaling that is critical for proliferation and survival of leukemic cells in many B cell malignancies. BTK was initially shown to be defective in the primary
Doorduijn, J.K. (Jeanette), Hiemcke-Jiwa, L.S. (Laura S.), Huibers, M.M.H. (Manon M. H.), Leguit, P. (Piet), Minnema, M.C. (Monique), Radersma-van Loon, J.H. (Joyce H.), Rood, J.J.M. (Johannes J. M.), Westerweel, J. (Jerry)   +7 more
core   +18 more sources

Bilateral central retinal vein occlusion as an initial presentation of Waldenström macroglobulinemia: a case report

Journal of Medical Case Reports, 2023
Background Waldenström macroglobulinemia is a rare hematological malignancy and is the most common diagnosis in patients with hyperviscosity syndrome.
Suraj Shrestha, Elisha Poddar, Bibhav Bashyal, Aayush Adhikari, Prabin Pathak, Suman Acharya, Surendra Sapkota, Anjan Bhattarai, Samriddha Raj Pant, Anjan Shrestha   +9 more
doaj   +1 more source

Ibrutinib effect in acquired von Willebrand syndrome secondary to Waldenström macroglobulinemia

Therapeutic Advances in Hematology, 2021
The pathological increase of clonal IgM in Waldenström macroglobulinemia can be associated with acquired von Willebrand syndrome and can be a major risk of bleeding symptoms in this subgroup of patients with Waldenström macroglobulinemia.
María Poza, Rodrigo Íñiguez, Irene Zamanillo, Sara Redondo, Rafael Alonso, Joaquín Martínez-López, Ana Jiménez-Ubieto   +6 more
doaj   +1 more source

A rare clinical presentation of Waldenström Macroglobulinemia mimicking lung cancer

Respiratory Medicine Case Reports, 2022
Waldenström macroglobulinemia rarely presents as pulmonary symptoms, and even rarer as chylothorax. We present a patient who presented with bilateral pleural effusion and a 30 mm solid lesion in the lung.
Michael RT. Laursen, Shailesh Kolekar, Pradeesh Sivapalan, Paul F. Clementsen, Uffe Bodtger   +4 more
doaj   +1 more source

Increased plasma viscosity as a reason for inappropriate erythropoietin formation [PDF]

, 1993
The aim of this study was to examine whether altered plasma viscosity could contribute to the inappropriately low production rate of erythropoietin (EPO) observed in patients suffering from hypergammaglobulinemias associated with multiple myeloma or ...
Eckardt, Kai-Uwe, Götz, Karlheinz, Hamann, M., Kurtz, Armin, Ratcliffe, P. J., Reinhart, W. H., Singh, A., Zimmermann, A.   +7 more
core   +2 more sources

Pattern of somatic mutations in patients with Waldenström macroglobulinemia or IgM monoclonal gammopathy of undetermined significance

Haematologica, 2017
We analyzed MYD88 and CXCR4 mutation status of 260 patients with Waldenström macroglobulinemia or IgM monoclonal gammopathy of undetermined significance using allele-specific real time quantitative polymerase chain reaction and Sanger sequencing ...
Marzia Varettoni, Silvia Zibellini, Irene Defrancesco, Virginia Valeria Ferretti, Ettore Rizzo, Luca Malcovati, Anna Gallì, Matteo Giovanni Della Porta, Emanuela Boveri, Luca Arcaini, Chiara Candido, Marco Paulli, Mario Cazzola   +12 more
doaj   +1 more source

Multimodal Imaging of Waldenstrom Macroglobulinemia-Associated Hyperviscosity-Related Retinopathy Treated with Plasmapheresis

Case Reports in Ophthalmological Medicine, 2021
While plasmapheresis is well known to significantly improve both retinal findings and systemic manifestations associated with Waldenstrom macroglobulinemia, few reports exist documenting changes in optical coherence tomography angiography (OCT-A).
Michael J. Schatz, Carl S. Wilkins, Oscar Otero-Marquez, Toco Y. P. Chui, Richard B. Rosen, Meenakashi Gupta   +5 more
doaj   +1 more source