Results 191 to 200 of about 1,051,412 (371)
In this study, Acod1 knockout in CLP mice significantly increases peripheral blood NET levels, exacerbating inflammation, organ damage, and reducing survival. Further research shows that UBR5 interacts with PAD4, a key NET formation protein. Acod1/itaconate (ITA) enhances the enzymatic activity of UBR5 by alkylating the Cys2768 site, promoting the K48 ...
Huifan Liu+10 more
wiley +1 more source
Capillary zone and agarose plasma protein electrophoresis in the sand tiger shark (<i>Carcharias taurus</i>). [PDF]
Cray C+5 more
europepmc +1 more source
The tumor‐associated macrophages (TAMs) in lung cancer tissues exhibit active cystine metabolism. Restricting cystine concentration in macrophages induces M1 phenotypic polarization and upregulation of PD‐L1 expression through the GSH‐NF‐κB signaling pathway.
Yun Xu+20 more
wiley +1 more source
CCDC183‐AS1 overexpression enhanced the ability of PCa cells to spread to the bone by inducing osteoclastogenesis. Mechanistically, CCDC183‐AS1 interacted with FUBP1 and enhanced its stability, which promoted the transcription of TNFSF14 (LIGHT). Copy number gain‐induced KDM5C epigenetically upregulated CCDC183‐AS1 expression by recruiting TET1 to the ...
Chuandong Lang+10 more
wiley +1 more source
Dynamic monitoring of M-protein quantification by immunotyping using capillary zone electrophoresis during the chemotherapy of patients with multiple myeloma. [PDF]
Jia Z, Lu Q.
europepmc +1 more source
Novel detection method of aberrant blood proteins by electrophoresis and mass spectrometry.
Akira Shimizu
openalex +2 more sources
Revealing Cell‐Free Mitochondrial DNA Breakage Patterns as Novel Biomarkers for Sepsis
Uncovering distinct plasma cfmtDNA breakage patterns opens new frontiers for early sepsis detection and prognosis. Unique cleavage hotspots in RNR2 and COX2 regions outperform traditional biomarkers, while mechanistic insights suggest bacterial endonuclease involvement.
Haitang Liao+13 more
wiley +1 more source
Identification of Serum Biomarkers for Blast-induced Traumatic Brain Injuries: Low <i>vs</i>. High-intensity Exposure in a Rat Model. [PDF]
Bera A, Subhramanian M, Sharma P.
europepmc +1 more source