Results 171 to 180 of about 1,574,624 (315)

TLR4 Signaling by Heme and the Role of Heme-Binding Blood Proteins. [PDF]

Front Immunol, 2020
Janciauskiene S, Vijayan V, Immenschuh S.   +2 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

The role of lipid in malaria pigment (Haemozoin) formation under biomimetic conditions

, 2013
Includes bibliographical references.Previous studies have proposed lipids and/or proteins to be involved in the biomineralization process of haemozoin formation in the malaria parasite which is a target for many antimalarial drugs.
Ambele, Melvin Anyasi
core  

Proteome-wide Mendelian randomisation identifies causal links between blood proteins and myopia. [PDF]

J Glob Health
Wu F, Zhou Y, Ma X, Zhao Z, Wang S, Ma K, Yang S, Cao M, Yi G, Fu M.   +9 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

A study of the reactivity of benzyl-penicillin toward the components of human blood

, 1976
Benzylpenicillin is incubated with whole human blood. The degree of reactivity of 14C-benzylpenicillin to the components of this blood is determined via a Beckman LS-100C Liquid Scintillation Counter.The oxygen carrying capacities of penicillin treated ...
Talbert, Madonna L.
core  

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Ambient temperature exposure on inflammatory blood proteins-A longitudinal self-sampling survey in young Swedish adults. [PDF]

iScience
Yu Z, Björkander S, Bendes A, Nobile F, Zhang J, Merid SK, Hernandez-Pacheco N, He S, Kere MM, Klevebro S, Ljungman P, Stafoggia M, Bellander T, Pershagen G, Bergström A, Kull I, Merritt AS, Roxhed N, Gruzieva O, Schwenk JM, Melén E.   +20 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Catalytically Active Recombinant Cysteine Proteases of <i>Haemonchus contortus:</i> Their Ability to Degrade Host Blood Proteins and Modulate Coagulation. [PDF]

Int J Mol Sci
Karunakaran AC, Bakshi M, Rajendrakumar AM, Wilson-Welder JH, Aroian RV, Schwarz EM, Homan EJ, Ostroff GR, Beshah E, Miramontes E, Papadopoulos MD, Bowdridge SA, Zarlenga DS, Zhu X, Tuo W.   +14 more
europepmc   +1 more source