Results 11 to 20 of about 1,574,624 (315)

Proteomics-Based Detection of Immune Dysfunction in an Elite Adventure Athlete Trekking Across the Antarctica

Proteomes, 2020
Proteomics monitoring of an elite adventure athlete (age 33 years) was conducted over a 28-week period that culminated in the successful, solo, unassisted, and unsupported two month trek across the Antarctica (1500 km).
David C. Nieman, Arnoud J. Groen, Artyom Pugachev, Andrew J. Simonson, Kristine Polley, Karma James, Bassem F. El-Khodor, Saradhadevi Varadharaj, Claudia Hernández-Armenta   +8 more
doaj   +1 more source

Vascular Effects on Cerebrovascular Permeability and Neurodegeneration

Biomolecules, 2023
Neurons and glial cells in the brain are protected by the blood brain barrier (BBB). The local regulation of blood flow is determined by neurons and signal conducting cells called astrocytes.
Nurul Sulimai, Jason Brown, David Lominadze   +2 more
doaj   +1 more source

Structure of Human ATG9A, the Only Transmembrane Protein of the Core Autophagy Machinery

Cell Reports, 2020
Summary: Autophagy is a catabolic process involving capture of cytoplasmic materials into double-membraned autophagosomes that subsequently fuse with lysosomes for degradation of the materials by lysosomal hydrolases.
Carlos M. Guardia, Xiao-Feng Tan, Tengfei Lian, Mitra S. Rana, Wenchang Zhou, Eric T. Christenson, Augustus J. Lowry, José D. Faraldo-Gómez, Juan S. Bonifacino, Jiansen Jiang, Anirban Banerjee   +10 more
doaj   +1 more source

A Fast and Reliable Method Based on QCM-D Instrumentation for the Screening of Nanoparticle/Blood Protein Interactions

Biosensors, 2023
The interactions that nanoparticles have with blood proteins are crucial for their fate in vivo. Such interactions result in the formation of the protein corona around the nanoparticles, and studying them aids in nanoparticle optimization. Quartz crystal
Mariacristina Gagliardi, Laura Colagiorgio, Marco Cecchini   +2 more
doaj   +1 more source

von Willebrand factor binds to the surface of dendritic cells and modulates peptide presentation of factor VIII

Haematologica, 2016
It has been proposed that von Willebrand factor might affect factor VIII immunogenicity by reducing factor VIII uptake by antigen presenting cells. Here we investigate the interaction of recombinant von Willebrand factor with immature monocyte-derived ...
Nicoletta Sorvillo, Robin B. Hartholt, Esther Bloem, Magdalena Sedek, Anja ten Brinke, Carmen van der Zwaan, Floris P. van Alphen, Alexander B. Meijer, Jan Voorberg   +8 more
doaj   +1 more source

Salivary gland proteins of the human malaria vector, Anopheles dirus B (Diptera Culicidae) [PDF]

, 2007
Salivary gland proteins of the human malaria vector, Anopheles dirus B were determined and analyzed. The amount of salivary gland proteins in mosquitoes aged between 3--10 days was approximately 1.08 +/- 0.04 microg/female and 0.1 +/- 0.05 microg/male ...
Mark C. Wilkinson, Bates, Paul A., Thasaneeya Harnnoi, Choochote, Wej, Anuluck Junkum, Wilkinson, Mark, Wilkinson, Mark C, Paul A. Bates, Wej Choochote, Siriyasatein, Padet, Atchariya Jitpakdi, Padet Siriyasatein, Harnnoi, Thasaneeya, Narissara Jariyapan, Jariyapan, Narissara, Bates, Paul A, Junkum, Anuluck, Jitpakdi, Atchariya   +17 more
core   +1 more source

Structural insight into mitochondrial β-barrel outer membrane protein biogenesis

Nature Communications, 2020
The Sorting and Assembly Machinery (SAM) complex folds beta-barrel proteins and inserts them into the mitochondrial outer membrane. Here authors report cryoEM structures of the SAM complex from Myceliophthora thermophila, which reveals a GST-like fold ...
Kathryn A. Diederichs, Xiaodan Ni, Sarah E. Rollauer, Istvan Botos, Xiaofeng Tan, Martin S. King, Edmund R. S. Kunji, Jiansen Jiang, Susan K. Buchanan   +8 more
doaj   +1 more source

Tin speciation in the blood plasma of workers occupationally exposed in a cassiterite ore processing industry [PDF]

Saúde em Debate, 2022
Mining is a high-risk activity due to its dangerous processes. Tin (Sn) is obtained from cassiterite ore and mining activities expose workers to the metal. Chronic exposure to Sn may cause pneumoconiosis, gastrointestinal and hematological effects, among
Débora Resende de Souza Lima, Filipe Soares Quirino da Silva, Renato Marçullo borges, Rejane Correa Marques, Maria de Fátima Ramos Moreira   +4 more
doaj   +1 more source

A subset of anti-HLA antibodies induces FcγRIIa-dependent platelet activation

Haematologica, 2018
HLA antibodies are associated with refractoriness to platelet transfusion, leading to rapid platelet clearance, sometimes coinciding with clinical side effects such as fever and chills.
Maaike Rijkers, Anno Saris, Sebastiaan Heidt, Arend Mulder, Leendert Porcelijn, Frans H.J. Claas, Ruben Bierings, Frank W.G. Leebeek, A.J. Gerard Jansen, Gestur Vidarsson, Jan Voorberg, Masja de Haas   +11 more
doaj   +1 more source

SOME PHYSIOLOGICAL AND BIOCHEMICAL RESPONSES OF GROWING MALE SYRIAN GABALY GOATS AS AFFECTED BY SEASONAL CLIMATIC CHANGES IN THE NEWLY RECLAIMED AREAS. [PDF]

Journal of Animal and Poultry Production, 2008
The present study was carried out at Maryout Research Station (32˚n latitude, 35 km southwest of Alexandria) which belongs to the DesertResearchCenter, Ministry of Agriculture and Land Reclamation.
E. Taha, H. Shedeed, Y. Shaker, M. El-Ganaieny, E. Abdalla,   +4 more
doaj   +1 more source