Results 191 to 200 of about 11,282,122 (391)

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Machine Learning of ZnO Interaction with Immunoglobulins and Blood Proteins in Medicine.

J Healthc Eng, 2022
Qader Osman NA, Al-Ziyadi SH, Alazzam MB, Alshawwa SZ, Rahman MA.   +4 more
europepmc   +1 more source

Host blood proteins as bridging ligand in bacterial aggregation as well as anchor point for adhesion in the molecular pathogenesis of Staphylococcus aureus infections. [PDF]

Micron, 2021
Casillas-Ituarte NN, Staats AM, Lower BH, Stoodley P, Lower SK.   +4 more
europepmc   +1 more source

THE PLASMA PROTEINS IN RELATION TO BLOOD HYDRATION [PDF]

, 1925
John P. Peters, Anna J. Eisenman, Harold A. Bulger   +2 more
openalex   +1 more source

Blood coagulation control proteins.

Nihon Naika Gakkai Zasshi, 1994
血液凝固と凝固制御反応は,正常時における血液の流動性の維持と傷害時における止血と組織修復に不可欠な生体防御反応である.最近の臨床研究により,血栓形成の制御・調節における凝固制御蛋白の重要性が明らかになってきた.凝固制御蛋白の作用機序は多様で, 1)プロテアーゼとして作用して凝固因子を分解する(プロテインC), 2)補酵素蛋白として作用してプロテアーゼの活性を高める(トロンボモジュリン,プロテインS), 3)プロテアーゼインヒビターとして作用して活性化凝固因子を阻害する(アンチトロンビンIII,組織因子系凝固インヒビター)などがある.これらの蛋白は血小板や血管内皮などの細胞膜リン脂質や細胞膜上のヘパリン様物質に結合して活性発現する.本稿では,生理的に重要な凝固制御蛋白の構造と機能の関係 ...
openaire   +2 more sources

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

Concerning the Relative Magnitude of the Parts Played by the Proteins and by the Bi-Carbonates in the Maintenance of the Neutrality of the Blood

, 1910
T. Brailsford Robertson
openalex   +1 more source

The conversion of cyanogen chloride to cyanide in the presence of blood proteins and sulphydryl compounds [PDF]

, 1951
W. N. Aldridge
openalex   +1 more source

Harnessing the Potential of Blood Proteins as Functional Ingredients: A Review of the State of the Art in Blood Processing.

Comprehensive Reviews in Food Science and Food Safety, 2017
Sarah A. Lynch, A. Mullen, Eileen E. O'Neill, C. A. García   +3 more
semanticscholar   +1 more source