Results 101 to 110 of about 4,481,355 (305)

Automated drug screening of dried blood spots using online LC-MS/MS analysis

open access: yes, 2020
2 figuras, 2 tablasA fully automated method for the effective drug screening of large populations based on dried blood spot (DBS) technology is presented.
Cebolla, Vicente L.   +3 more
core  

Screening for congenital hypothyroidism in Maltese newborns using cord blood [PDF]

open access: yes, 1996
Routine screening for congenital hypothyroidism (CHT) has been introduced because clinical features of CHT may not be evident before the baby is a few weeks old and treatment at this stage may already be too late.
Rizzo, M.   +3 more
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

[Health promotion strategy 2004] / Irish Cervical Screening Programme

open access: yes, 2004
Irish Cervical Screening ...
Irish Cervical Screening Programme (ICSP)
core  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Reentry of voluntary blood donors in Chongqing, China (2022–2024): a retrospective single-center analysis

open access: yesFrontiers in Medicine
This study presents a retrospective analysis of the reentry process for voluntary blood donors in Chongqing, China, from 2022 to 2024, focusing on donor profiles, requalification outcomes, and factors influencing successful return to donation.
Weifei Qin   +4 more
doaj   +1 more source

Regulation of blood-screening in vitro diagnostics in sub-Saharan African countries remains a challenge. [PDF]

open access: yesFront Med (Lausanne), 2023
Abdurrahman G   +7 more
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

The management of blood donors tested reactive to HCV in blood screening based on confirmation of HCV infection

open access: yesZhongguo shuxue zazhi
[Objective] To explore the management of blood donors tested reactive to HCV in blood screening based on confirmation of HCV infection. [Methods] Multiple HCV antibody assays, repeating HCV RNA testing, follow-up of blood donors and retesting of archive ...
DENG Xuelian   +6 more
doaj   +1 more source

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