Results 111 to 120 of about 4,481,355 (305)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Analysis of repeated nucleic acid test results in blood donors with dual-reactive enzyme-linked immunosorbent assay results and nonreactive nucleic acid test results

Zhongguo shuxue zazhi
[Objective] To investigate the impact of current laboratory testing models and screening strategies on blood safety by analyzing repeat nucleic acid testing (NAT) results obtained from blood donors who had dual-reactive enzyme-linked immunosorbent assay (
ZANG Liang, ZHOU Lei, LIU Xiaochun, SUN Peng, FAN Yaxin, LIANG Xiaohua   +5 more
doaj   +1 more source

Standardized evaluation of Zika nucleic acid tests used in clinical settings and blood screening. [PDF]

PLoS Negl Trop Dis, 2023
Stone M, Bakkour S, Grebe E, Emperador DM, Escadafal C, Deng X, Dave H, Kelly-Cirino C, Lackritz E, Rojas DP, Simmons G, Rabe IB, Busch MP.   +12 more
europepmc   +1 more source

A deep learning approach to prediction of blood group antigens from genomic data [PDF]

BACKGROUND: Deep learning methods are revolutionizing natural science. In this study, we aim to apply such techniques to develop blood type prediction models based on cheap to analyze and easily scalable screening array genotyping platforms.METHODS ...
Ritari, Jarmo, Ostrowski, Sisse R., Hyvärinen, Kati, Pedersen, Ole B., Sækmose, Susanne, Erikstrup, Christian, Brodersen, Thorsten, Bay, Jakob T., Bruun, Mie T., Olsson, Martin L., Larsen, Rune, Didriksen, Maria, Partanen, Jukka, Ullum, Henrik, Moslemi, Camous, Nielsen, Kaspar R., Dinh, Khoa M., Dowsett, Joseph, Mikkelsen, Christina, Saekmose, Susanne, Didriksen, Maria,, Bruun, Mie T.,, Larsen, Rune,, Ostrowski, Sisse R.,, Hyvärinen, Kati,, Moslemi, Camous,, Dowsett, Joseph,, Pedersen, Ole B.,, Brodersen, Thorsten,, Ritari, Jarmo,, Ullum, Henrik,, Partanen, Jukka,, Dinh, Khoa M.,, Bay, Jakob T.,, Olsson, Martin L.,, Mikkelsen, Christina,, Nielsen, Kaspar R.,, Erikstrup, Christian,, Sækmose, Susanne,, Lund University.   +39 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Congress report: Online workshop on assessment of technical files for blood screening in vitro diagnostics for sub-Sahara African countries. [PDF]

Transfus Med, 2022
Mbunkah HA, Kafere C, Samukange W, Nübling M, Reinhardt J.   +4 more
europepmc   +1 more source

Surveillance of HIV-1 genetic subtypes and diversity in the US blood supply

, 2000
BACKGROUND: Recent reports of variant (non-subtype B) HIV infections in US populations have raised concerns about the sensitivity of subtype B virus-based donor screening and diagnostic assays.
Finlayson, T., Gwinn, M., Busch, M. P., Sullivan, M. T., Oliveira, C. F. de, Machado, D. M., Kessler, D., Lackritz, E. M., Operskalski, E. A., Williams, A. E., Mosley, J. W., Diaz, R. S.   +11 more
core   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Donated Blood Screening for HIV, HCV and HBV by ID-NAT and the Residual Risk of Iatrogenic Transmission in a Tertiary Care Hospital Blood Bank in Puebla, Mexico. [PDF]

Viruses, 2023
Sosa-Jurado F, Palencia-Lara R, Xicoténcatl-Grijalva C, Bernal-Soto M, Montiel-Jarquin Á, Ibarra-Pichardo Y, Rosas-Murrieta NH, Lira R, Cortes-Hernandez P, Santos-López G.   +9 more
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source