Results 31 to 40 of about 4,938,056 (290)

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Effect of laser on erythrocytes sedimentation rate and some hematological parameters

open access: yesمجلة كلية الطب, 2017
Background: This study was conducted in pursuit of gaining an understand effects of the low level laser irradiation on whole blood is very essential way in revealing the mechanisms of the action of laser radiation  on biological tissues.
Eman A. Shaker   +2 more
doaj   +1 more source

Hematology Profile Analysis and Birth Weight in Preeclampsia [PDF]

open access: yesE3S Web of Conferences, 2020
Preeclampsia is a specific syndrome in pregnancy that occur after 20 weeks gestation in women who were previously normotensive. Hypertension in pregnancy caused complications in cardiovascular, hematology, endocrine, metabolic and regional blood flow ...
Eko Martanti Listyaning   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Use of C-reactive protein in pediatric patients with renal diseases

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2017
Background: the use of C-reactive protein as an inflammatory marker in various conditions is part of novel studies in the field of many specialties such as cardiology and immunology.Objective: to assess the usefulness of C-reactive protein for the ...
Elizabeth Vidor Guerra   +4 more
doaj  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

A Relationship between the Obstructive Sleep Apnea Syndrome and the Erythrocyte Sedimentation Rate [PDF]

open access: yesClinical and Experimental Otorhinolaryngology, 2009
ObjectivesThe erythrocyte sedimentation rate (ESR) is a marker for inflammation, and it has been identified as a risk factor for atherothrombotic cardiovascular disease. The aim of this study was to determine the relationship between the plasma ESR level
Jin-Young Min   +6 more
doaj   +1 more source

Sedimentation of Blood Corpuscles [PDF]

open access: yesNature, 1920
I HAVE noticed lately that if oxalated or defibrinated Wood is put to stand in narrow tubes, the corpuscles sediment a good deal faster if the tube is inclined than when it is vertical. Thus with tubes about 2.7 mm. internal diameter there were, after 20 hours, 4, 23, 35, and 42 per cent of clear serum with tubes inclined at 0°, 221/3°, 45°, and 671/2°
openaire   +2 more sources

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