Results 41 to 50 of about 127,182 (291)

Use of C-reactive protein in pediatric patients with renal diseases

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2017
Background: the use of C-reactive protein as an inflammatory marker in various conditions is part of novel studies in the field of many specialties such as cardiology and immunology.Objective: to assess the usefulness of C-reactive protein for the ...
Elizabeth Vidor Guerra, Martha Socarrás Conde, Kirenia Méndez Amador, Guillermo Rivero Feixas, Oscar Pérez Morales   +4 more
doaj  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

A Relationship between the Obstructive Sleep Apnea Syndrome and the Erythrocyte Sedimentation Rate [PDF]

Clinical and Experimental Otorhinolaryngology, 2009
ObjectivesThe erythrocyte sedimentation rate (ESR) is a marker for inflammation, and it has been identified as a risk factor for atherothrombotic cardiovascular disease. The aim of this study was to determine the relationship between the plasma ESR level
Jin-Young Min, Jeon Yeob Jang, Hyo Yeol Kim, Won Yong Lee, Hun-Jong Dhong, Seung Kyu Chung, Soo-Chan Chung   +6 more
doaj   +1 more source

Erythrocyte sedimentation rate and blood viscosity as modified by fat emulsions

, 1960
The effect of lecithin and lecithin-free intravenous fat emulsions on erythrocyte sedimentation and blood viscosity was investigated. Lecithin-emulsified cottonseed oil markedly depressed erythrocyte sedimentation and increased blood viscosity of human ...
Isidore Cohn, Quentin L. Hartwig
core   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Simulation of the Separation of Homogeneous Whole Blood in a Spin-up Rotating Cylindrical Container [PDF]

Journal of Applied Fluid Mechanics
Centrifugal separation is a highly efficient technique for accelerating the sedimentation of blood constituents in a cylindrical container through high-speed spin-up rotation.
J. S. Fan, L. L. Xiao, C. S. Lin, P. Wei, K. X. Zhang   +4 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Separation of blood microsamples by exploiting sedimentation at the microscale

, 2018
Microsample analysis is highly beneficial in blood-based testing where cutting-edge bioanalytical technologies enable the analysis of volumes down to a few tens of microliters.
D. Forchelet, Liu, Y, Bararpour, N., Augsburger, M., Grabherr, Silke, Renaud, Philippe, R. Aebersold, P. Renaud, Augsburger, Marc, M. Augsburger, T. Sajic, Forchelet, David, Grabherr, S., Pataky, Z., Déglon, J., Frias, Miguel, M. Frias, S. Grabherr, Charnley, M, Béguin, Steve, Aebersold, R., Thomas, A., Sajic, T, N. Bararpour, Z. Pataky, M. Charnley, Renaud, P., Thomas, Aurélien, Liu, Y., Déglon, Julien, Aebersold, Ruedi, Forchelet, D, Forchelet, D., S. Béguin, Sajic, T., Pataky, Zoltan, Béguin, S., Charnley, M., Aebersold, R, Charnley, Mirren, Renaud, P, A. Thomas, J. Déglon, Sajic, Tatjana, Y. Liu, Béguin, S, Frias, M., Bararpour, N   +47 more
core   +2 more sources

The sample processing time interval as an influential factor in flow cytometry analysis of lymphocyte subsets

Memorias do Instituto Oswaldo Cruz, 2007
The objective of this paper is to propose a protocol to analyze blood samples in yellow fever 17DD vaccinated which developed serious adverse events. We investigated whether or not the time between sample collection and sample processing could interfere ...
Ana Paula dos Santos, Álvaro Luiz Bertho, Reinaldo de Menezes Martins, Rugimar Marcovistz   +3 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source