Results 81 to 90 of about 196,930 (302)

Neurological, psychological, and cognitive disorders in patients with chronic kidney disease on conservative and replacement therapy [PDF]

, 2016
Chronic kidney disease (CKD) is a highly prevalent condition in the world. Neurological, psychological, and cognitive disorders, related to CKD, could contribute to the morbidity, mortality, and poor quality of life of these patients.
Aceto, Paola, Carta, Maria, Davi, Leonardo, Frassetti, Nicla, Galani, Alessandro, Lai, Carlo, Lai, Silvia, Mariotti, Amalia, Mecarelli, Oriano, Mitterhofer, Anna Paola, Poli, Luca, Pulitano, Patrizia, Romanello, Roberto, Tasso, Giorgia, Testorio, Massimo, Zarabla, Alessia   +15 more
core   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Chemical analysis of soluble fractions from normal and autolysed rabbit liver by column chromatography [PDF]

, 1966
Chromatography on Sephadex G-200 was performed with the soluble fraction of homogenated rabbit liver, which was extracted with 0.1 M phosphate buffer containing 0.1 M NaCl.
Aizawa, Tadashi, Matsuura, Yasushi, Yamamoto, Saburo, Yamamoto, Yasuhisa, Yoshikawa, Satoshi   +4 more
core   +1 more source

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons, Todd Levine, Charles H. Adler, Bailey Bellaire, Ningshan Wang, Pinky Agarwal, Georgina M. Aldridge, Alexandru Barboi, Daniel Claassen, Virgilio G. H. Evidente, Douglas Galasko, Alejandra Gonzalez‐Duarte, Ramon Gil, Mark Gudesblatt, Stuart H. Isaacson, Horacio Kaufmann, Pravin Khemani, Rajeev Kumar, Guillaume Lamotte, Andy J. Liu, Nikolaus R. McFarland, Mitchell G. Miglis, Adam Reynolds, Gregory A. Sahagian, Marie‐Helene Saint‐Hilaire, Julie B. Schwartzbard, Wolfgang Singer, Michael J. Soileau, Steven Vernino, Patricio Millar Vernetti, Oleg Yerstein, Roy Freeman   +31 more
wiley   +1 more source

Biochemical Evaluation of Withania Somnifera Root Powder on Adjuvant-Induced Arthritis in Rats [PDF]

, 2015
The present investigation was carried out to evaluate the biochemical effect of Withania somnifera Linn. Solanaceae, commonly known as ashwagandha on adjuvant induced arthritic rats.
Rasool, M. (Mahaboobkhan), Varalakshmi, P. (Palaninathan)   +1 more
core  

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa, Iago Pinal‐Fernandez, Pritikanta Paul, Michael P. Skolka, Margherita Milone, Min Shi, Mithun V. Shah, Maria Casal‐Dominguez, Katherine Pak, Andrew L. Mammen, Teerin Liewluck   +10 more
wiley   +1 more source

Traumatic Microhemorrhages Are Not Synonymous With Axonal Injury

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diffuse axonal injury (DAI) is caused by acceleration‐deceleration forces during trauma that shear white matter tracts. Susceptibility‐weighted MRI (SWI) identifies microbleeds that are considered the radiologic hallmark of DAI and are used in clinical prognostication.
Karinn Sytsma, Rhonda Mittenzwei, Heather Maioli, Amanda Kirkland, C. Dirk Keene, Ramon Diaz‐Arrastia, Christine Mac Donald, Chiara Maffei, Brian L. Edlow, Amber L. Nolan   +9 more
wiley   +1 more source

Blood group antigens visualisation on leukocytes [PDF]

Scripta Medica
Background/Aim: The leukocytes have been reported to contain blood group specific antigens, that are clinically relevant, however visualisation of A and B group antigens on leukocytes is a big issue.
Grigorovich Kravchun Pavlo, Solomonivna Leontyeva Frida, Dmytrivna Povelichenko Olena, Yuriivna Dielievska Valentyna   +3 more
doaj   +1 more source

Validity of a three-variable juvenile arthritis disease activity score in children with new-onset juvenile idiopathic arthritis [PDF]

, 2012
<p>Objectives To investigate the validity and feasibility of the Juvenile Arthritis Disease Activity Score (JADAS) in the routine clinical setting for all juvenile idiopathic arthritis (JIA) disease categories and explore whether exclusion of the ...
Adib, Aletaha, Bazso, Beresford, Consolaro, Eileen M Baildam, Flora Mcerlane, Fuchs, Fuchs, Helen E Foster, Hyrich, Janet Gardner-Medwin, Joyce E Davidson, Kimme L Hyrich, Leeb, Lucy R Wedderburn, Magni-Manzoni, Mark Lunt, Michael W Beresford, Nordal, Nordal, Nugent, Petty, Petty, Ringold, S E Alice Chieng, Symmons, Wendy Thomson   +27 more
core   +2 more sources