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Blood Transfusion or Blood Substitution?
Vox Sanguinis, 1986Abstract. Blood transfusion has become a universally accepted, life‐saving procedure in modern clinical medicine. In addition, specific blood fractions are widely used in the therapeutic treatment of haematological disorders. Problems are, however, encountered in conventional transfusion practice and in the clinical use of blood components.
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Artificial Cells, Blood Substitutes, and Biotechnology, 1998
Soluble polymerized haemoglobin (polyhaemoglobin) is now in a phase III clinical trials. Patients have received up to 20 units (10 litres) in trauma surgery and other surgery. Polyhaemoglobin can be stored for more than 1 year. Haemoglobin solutions have no blood group antigen and can be used as a 'universal donor' oxygen carrier.
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Soluble polymerized haemoglobin (polyhaemoglobin) is now in a phase III clinical trials. Patients have received up to 20 units (10 litres) in trauma surgery and other surgery. Polyhaemoglobin can be stored for more than 1 year. Haemoglobin solutions have no blood group antigen and can be used as a 'universal donor' oxygen carrier.
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Biological Reviews, 1937
Summary Solutions of crystalloids cannot be considered as substitutes for mammalian blood since they quickly leave the blood stream and are unable to maintain blood volume and pressure. This is true even of hypertonic solutions. The only effective blood substitutes are those which contain sufficient colloidal material to give a colloidal osmotic ...
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Summary Solutions of crystalloids cannot be considered as substitutes for mammalian blood since they quickly leave the blood stream and are unable to maintain blood volume and pressure. This is true even of hypertonic solutions. The only effective blood substitutes are those which contain sufficient colloidal material to give a colloidal osmotic ...
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Microparticle, nanoparticle, and stem cell-based oxygen carriers as advanced blood substitutes.
Trends in Biotechnology, 2014Zhimin Tao +2 more
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Multilayered Hollow Tubes as Blood Vessel Substitutes.
ACS Biomaterials Science & Engineering, 2016Joana M. Silva +3 more
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Construction and Evaluation of Hemoglobin‐Based Capsules as Blood Substitutes
, 2012Yi Jia +6 more
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