Results 171 to 180 of about 749,253 (353)

Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism

open access: yesAdvanced Science, EarlyView.
Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang   +4 more
wiley   +1 more source

Deficiency of SCAMP5 Triggers Pancreatic β‐Cell Secretory Dysfunction and Apoptosis

open access: yesAdvanced Science, EarlyView.
This study demonstrates that hyperglycemia in diabetes activates ChREBP, which epigenetically represses SCAMP5 expression in pancreatic β‐cells. This SCAMP5 deficiency impairs insulin secretion by downregulating the calcium channel CaV1.2. Furthermore, reduced SCAMP5 triggers β‐cell apoptosis by stabilizing VDAC1 and enhancing its interaction with Bax,
Yingqi Zhang   +10 more
wiley   +1 more source

"Failure to control blood sugar" experiences of persons with type 2 diabetes mellitus. [PDF]

open access: yesInt J Nurs Sci, 2023
Numsang P   +5 more
europepmc   +1 more source

Closed‐Loop Bioelectronic Artificial Pancreas Patch for Continuous Monitoring and Regulation of Blood Glucose in Diabetic Rats and Pigs

open access: yesAdvanced Science, EarlyView.
A closed‐loop bioelectronic artificial pancreas patch is presented for glucose monitoring and regulation. Utilizing transiently dissolvable microneedle arrays integrated with microtube arrays, the patch efficiently delivers insulin into interstitial fluid, eliminating the need for external long needles. In diabetic pigs, it demonstrates excellent blood
Yiqun Liu   +9 more
wiley   +1 more source

Effect of Topical Mometasone Furoate Cream (0.01 % w/w) on Blood Pressure, Blood Sugar and Blood Calcium Level

open access: yesWalawalkar International Medical Journal
Background: Corticosteroids are commonly administered for skin diseases over short durations, typically ranging from a few days to a few weeks. The choice of corticosteroid is based on its potency, which is determined by the application site and ...
Chetan Javsen, Avanti Ghadage
doaj  

Targeting Multilayered Metabolic Networks in Brain Diseases: Emerging Perspectives on Nanodelivery Strategies

open access: yesAdvanced Science, EarlyView.
Brain diseases involve multilayered metabolic disruptions that reshape cellular interactions and microenvironments. This review outlines core metabolic features across disease states and presents emerging nanodelivery strategies as precision tools to reprogram pathological metabolism.
Jingyi Zhou, Chen Jiang
wiley   +1 more source

Elevated Blood Pressure, Abnormal Urinalysis and Body Mass Index as Screening Tools for Latent Kidney Diseades Among Adolescents in Sagamu

open access: yesAnnals of Health Research, 2015
Background: The prevalence of non-communicable diseases, such as chronic kidney diseases, is on the increase globally. Therefore, early identification of these conditions through routine screening is desired as a preventive measure.
Adekanmbi AF   +3 more
doaj  

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