Results 31 to 40 of about 3,200,961 (292)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Anti-fatigue effect of hemp seed oligopeptide in mice and its sex difference

Shipin yu jixie
Objective: To explore the anti-fatigue effect of hemp seed oligopeptides, and its effect and mechanism between male and female individuals. Methods: Equal number of male and female mice were randomly divided into a blank control group, a positive control
MIAO Wenyu, LI Yunfei, SONG Lulu, WANG Jingjing, CHENG Jianjun, QIN Nan   +5 more
doaj   +1 more source

Multifunctional Neutrophil Nanovesicles Induce Remodeling of Tumor Immune Microenvironment and Synergistic Multimodal Tumor Therapy

Advanced Functional Materials, EarlyView.
Schematic illustration of the engineered RN@FDT for multimodal tumor therapy. a) Fabrication of FD&DOX/TFA‐loaded RGD‐NNV (RN@FDT) and the light‐triggered disassemble of RN@FDT. b) After internalized by tumor cells, RN@FDT are disintegrated under NIR‐II laser irradiation to boost PTT and induce cell apoptosis.
Jiahui Zhang, Cheng Ji, Xin‐Jian Fang, Yu Qian, Jiayuan Shi, Wenhui Liu, Baiyuan Fan, Yuan Zhong, Jiayi Wang, Dan Yu, Maoye Wang, Min Fu, Xiaoxin Zhang, Runbi Ji, Hélder A. Santos, Hongbo Zhang, Xu Zhang   +16 more
wiley   +1 more source

The Effect of Submaximal Exercise on Blood Creatinine, Urea, Total Protein and Uric Acid Levels of Trained and Untrained Subjects

Baltic Journal of Sport and Health Sciences, 2018
There are numerous studies about exercise-induced sports hematuria, proteinuria, acute renal failure following a marathon (Steward, Posen, 1980; Poortmans et al., 2001; Ayca et al., 2006).
Alina Gailiūnienė, Arvydas Stasiulis, Jolanta Michailovienė   +2 more
doaj   +1 more source

Effect of Dietary Urea in Gestating Beef Cows: Circulating Metabolites, Morphometrics, and Mammary Secretions

Animals, 2022
Prolific use of supplementation strategies, including the utilization of urea, are practiced in beef cattle production systems. Unfortunately, the influence of urea supplementation on metabolics, adipose tissue mobilization, and mammary secretions is ...
Ligia D. Prezotto, Jennifer F. Thorson
doaj   +1 more source

Nitrogen efficiency of dairy cattle : from protein evaluation to ammonia emission [PDF]

, 2011
Diet optimization contributes considerably to increased nitrogen efficiency of dairy cattle, resulting in reduced nitrogen losses. This thesis focuses on three themes: the potential advances in protein evaluation systems for ruminants, the relationship ...
van Duinkerken, G., Duinkerken, G., van
core  

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

Advanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang, Zhisheng Xu, Yaou Duan, Yehui Sun, Shiying Wu, Tao Long, Mateusz Durbacz, Li Zhang, Yufen Xiao, Yu‐Chung Pien, Erick D. Guerrero, Zeru Tian, Xu Wang, Pratima Basak, Sumanta Chatterjee, Ning Liu, Xiaochun Li, Eric N. Olson, Daniel J. Siegwart   +18 more
wiley   +1 more source

Blood profile, creatinine, and urea nitrogen levels in the blood of male duck fed noni leaf meal (Morinda citrifolia Linn) [PDF]

BIO Web of Conferences
The objective of this study was to assess the effect of noni leaf meal on the blood profile, creatinine, and urea nitrogen of male ducks at different levels of inclusion into the diet.
Hermana Widya, Asella, Suci Dwi Margi, Darmawan Arif   +3 more
doaj   +1 more source

Rare‐Earth–Functionalized Carbon Dot Hydrogels as Mechanically Robust Antibacterial Wound Dressings

Advanced Healthcare Materials, EarlyView.
The schematic depicts a dynamically cross‐linked PVA hydrogel network in which reversible borate ester bonds and hydrogen‐bonding interactions integrate lanthanum‐doped carbon dots (La‐CDs) and dipotassium glycyrrhizinate (DPG) to form a mechanically robust, multifunctional matrix.
Shih‐Han Tsai, Ramadhass Keerthika Devi, Muthusankar Ganesan, Guo‐Ping Chang Chien, Chun Che Lin   +4 more
wiley   +1 more source

A Coulometric Determination of Urea Nitrogen in Blood and Urine

Clinical Chemistry, 1965
Abstract To determine urea nitrogen, ammonia resulting from urease hydrolysis of urea is titrated with coulometrically generated hypobromite ion using a direct amperometric end-point detection. In blood samples, the ammonia is first separated by the microdiffusion technic. The ammonia may be titrated directly in urine samples.
G D, CHRISTIAN, E C, KNOBLOCK, W C, PURDY   +2 more
openaire   +2 more sources