Results 91 to 100 of about 5,657,221 (393)

Microstructured blood vessel surrogates reveal structural tropism of motile malaria parasites [PDF]

, 2017
Plasmodium sporozoites, the highly motile forms of the malaria parasite, are transmitted naturally by mosquitoes and traverse the skin to find, associate with, and enter blood capillaries.
Battista, Anna, Dahan, Noa, Fackler, Oliver T., Frischknecht, Friedrich, Haraszti, Tamas, Hellmann, Janina K., Lemgruber, Leandro, Muthinja, Mendi J., Ripp, Johanna, Schwarz, Ulrich S., Schütz, Lucas, Spatz, Joachim P.   +11 more
core   +1 more source

Dynamic stroma reorganization drives blood vessel dysmorphia during glioma growth

EMBO Molecular Medicine, 2017
Glioma growth and progression are characterized by abundant development of blood vessels that are highly aberrant and poorly functional, with detrimental consequences for drug delivery efficacy.
T. Mathivet, C. Bouleti, Matthias van Woensel, F. Stanchi, T. Verschuere, Li-Kun Phng, J. Dejaegher, Marly Balcer, Ken Matsumoto, Petya B Georgieva, J. Belmans, R. Sciot, C. Stockmann, M. Mazzone, S. De Vleeschouwer, H. Gerhardt   +15 more
semanticscholar   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

RhoA/rho-kinase, nitric oxide and inflammatory response in LIMA during OPCABG with isoflurane preconditioning

Journal of Cardiothoracic Surgery, 2019
Background Grafting vessel with LIMA to the left anterior descending coronary artery plays a most important role in the long-term prognosis of OPCABG surgery.
Liang Zhang, Cheng-Bin Wang, Bo Li, Duo-Mao Lin, Jun Ma   +4 more
doaj   +1 more source

Flow correlated percolation during vascular network formation in tumors

, 2005
A theoretical model based on the molecular interactions between a growing tumor and a dynamically evolving blood vessel network describes the transformation of the regular vasculature in normal tissues into a highly inhomogeneous tumor specific capillary
A.-L. Barabási, D. Stauffer, D.-S. Lee, H. Rieger, J. W. Baish, J. W. Baish, K. Bartha   +6 more
core   +1 more source

Blood vessel formation and function in bone

Development, 2016
In addition to their conventional role as a conduit system for gases, nutrients, waste products or cells, blood vessels in the skeletal system play active roles in controlling multiple aspects of bone formation and provide niches for hematopoietic stem ...
K. Sivaraj, R. Adams
semanticscholar   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

Blood Vessels [PDF]

Plastic and Reconstructive Surgery, 1976
J. T. Lie, L. P. Gordon, J. L. Titus, Constant Errikos   +3 more
  +6 more sources

Monocyte to high-density lipoprotein cholesterol ratio predicts poor outcomes in ischaemic heart failure patients combined with diabetes: a retrospective study

European Journal of Medical Research, 2023
Background The prevalence of ischaemic heart failure (HF) continues to increase. Diabetes mellitus (DM) concomitant with ischaemic HF increases the risk of major adverse cardiovascular events (MACEs). As a promising predictor for cardiovascular diseases,
Qiuyu Li, Xiaolong Lin, Xiaowen Bo, Fanqi Li, Siyuan Chen, Xuguang Miao, Donghui Zhao, Jinghua Liu, Qian Fan   +8 more
doaj   +1 more source