Results 71 to 80 of about 5,635,174 (391)

Association between cardiovascular-kidney-metabolic health metrics and long-term cardiovascular risk: Findings from the Chinese Multi-provincial Cohort Study

Chinese Medical Journal
. Background:. The American Heart Association (AHA) introduced the concept of cardiovascular-kidney-metabolic (CKM) health and stage, reflecting the interaction among metabolism, chronic kidney disease (CKD), and the cardiovascular system.
Ziyu Wang, Xuan Deng, Zhao Yang, Jiangtao Li, Pan Zhou, Wenlang Zhao, Yongchen Hao, Qiuju Deng, Na Yang, Lizhen Han, Yue Qi, Jing Liu, Rongman Jia   +12 more
doaj   +1 more source

ADRB2 polymorphisms and dyslipidemia risk in Chinese hypertensive patients

Clinical and Experimental Hypertension, 2017
Single nucleotide polymorphisms (SNPs) within a β-adrenergic receptor (ADRB2) were shown to be related to lipid traits or hyperlipidemia in different ethnicities, but not in a Chinese population. We performed the present study to investigate the possible
Wei Gu, Jilin Liu, Zuoguang Wang, Ya Liu, Shaojun Wen   +4 more
doaj   +1 more source

A simplified model for red cell dynamics in small blood vessels

, 1998
A simple mechanism for the confinement of red cells in the middle of narrow blood vessels is proposed. In the presence of a quadratic shear, red cells deform in such a way to loose fore-aft symmetry and to achieve a fixed orientation with respect to the ...
Olla, Piero
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Long term clinical outcome after success re-attempt percutaneous coronary intervention of chronic total occlusion

BMC Cardiovascular Disorders, 2023
Background To evaluate the long-term outcome after re-attempt CTO-PCI. Methods This is a retrospective cohort study that included 113 re-attempt CTO-PCI patients who were consecutively registered from January 2019 to December 2020 at Beijing Anzhen ...
Wenzheng Li, Zheng Wu, Tong Liu, Xiaofan Wu, Jinghua Liu   +4 more
doaj   +1 more source

Intramuscular Expression of Plasmid-Encoded FVII-Fc Immunoconjugate for Tumor Immunotherapy by Targeting Tumoral Blood Vessels and Cells [PDF]

, 2021
Liping Ma, Guanru Wang, Sijia Liu, Feng Bi, Ming Liu, Gang Wang, Gang Wang, Gang Wang   +7 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

The Level of Remnant Cholesterol and Implications for Lipid-Lowering Strategy in Hospitalized Patients with Acute Coronary Syndrome in China: Findings from the Improving Care for Cardiovascular Disease in China—Acute Coronary Syndrome Project

Metabolites, 2022
Elevated remnant cholesterol is associated with an increased risk of atherosclerotic cardiovascular disease (ASCVD). We aimed to evaluate the concentrations and general distribution of remnant cholesterol at admission in patients hospitalized for acute ...
Na Yang, Miao Wang, Jing Liu, Jun Liu, Yongchen Hao, Dong Zhao, on behalf of CCC-ACS Investigators   +6 more
doaj   +1 more source

Microstructured blood vessel surrogates reveal structural tropism of motile malaria parasites [PDF]

, 2017
Plasmodium sporozoites, the highly motile forms of the malaria parasite, are transmitted naturally by mosquitoes and traverse the skin to find, associate with, and enter blood capillaries.
Battista, Anna, Dahan, Noa, Fackler, Oliver T., Frischknecht, Friedrich, Haraszti, Tamas, Hellmann, Janina K., Lemgruber, Leandro, Muthinja, Mendi J., Ripp, Johanna, Schwarz, Ulrich S., Schütz, Lucas, Spatz, Joachim P.   +11 more
core   +1 more source

Dynamic stroma reorganization drives blood vessel dysmorphia during glioma growth

EMBO Molecular Medicine, 2017
Glioma growth and progression are characterized by abundant development of blood vessels that are highly aberrant and poorly functional, with detrimental consequences for drug delivery efficacy.
T. Mathivet, C. Bouleti, Matthias van Woensel, F. Stanchi, T. Verschuere, Li-Kun Phng, J. Dejaegher, Marly Balcer, Ken Matsumoto, Petya B Georgieva, J. Belmans, R. Sciot, C. Stockmann, M. Mazzone, S. De Vleeschouwer, H. Gerhardt   +15 more
semanticscholar   +1 more source