Results 101 to 110 of about 5,835,439 (392)

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

FEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto, Nobuko Koshikawa, Takao Morinaga, Mimi Tamamori‐Adachi, Atsushi Takatori, Keizo Takenaga   +5 more
wiley   +1 more source

Locating a blockage in the cerebral vascular network [PDF]

, 2011
Ischemic strokes make up 70-80% of strokes, and are characterised by blockages of arteries carrying blood to the brain. This problem involves the identification of blockages using a species distribution derived from an MRI scan of the brain.
McNamara, H.
core  

Deep convolutional neural networks for segmenting 3D in vivo multiphoton images of vasculature in Alzheimer disease mouse models

, 2019
The health and function of tissue rely on its vasculature network to provide reliable blood perfusion. Volumetric imaging approaches, such as multiphoton microscopy, are able to generate detailed 3D images of blood vessels that could contribute to our ...
Fang, Linjing, Haft-Javaherian, Mohammad, Muse, Victorine, Nishimura, Nozomi, Sabuncu, Mert R., Schaffer, Chris B.   +5 more
core   +2 more sources

Development of a model to demonstrate the effects of friction and pressure on skin in relation to pressure ulcer formation [PDF]

, 2017
© 2017 The Authors Pressure ulcers are a common injury of the skin which leads to pain and potential infection for patients and financial burden to the healthcare providers across the global due to treatment costs, litigation and extended hospital stays.
Amaied, Beckrich, Bennett, Bhattacharya, Black, Brem, Davis, Dealey, Dinsdale, Gorecki, Hwang, Krouskop, Liang, Linder-Ganz, Lévêque, Magnenat-Thalmann, Makhsous, Skobe, Szczerba, Vilhena, Xing, Yusuf, Zhong   +22 more
core   +1 more source

Accidental arterial puncture during right internal jugular vein cannulation in cardiac surgical patients

Annals of Cardiac Anaesthesia, 2016
Background: The primary aim of this study was to compare the incidence of accidental arterial puncture during right internal jugular vein (RIJV) cannulation with and without ultrasound guidance (USG).
Madan Mohan Maddali, Venkitaramanan Arun, Al-Ajmi Ahmed Wala, Maher Jaffer Al-Bahrani, Cheskey Manoj Jayatilaka, Arora Ram Nishant   +5 more
doaj   +1 more source

In vitro fabrication of functional three-dimensional tissues with perfusable blood vessels

Nature Communications, 2013
Artificially engineered tissues may have many therapeutic applications but complex tissues are hard to create in vitro. Here, Okano and colleagues report the production of functional cardiac tissue sheets with perfusable blood vessels, which increase the
H. Sekine, Tatsuya Shimizu, Katsuhisa Sakaguchi, Izumi Dobashi, Masanori Wada, M. Yamato, E. Kobayashi, M. Umezu, T. Okano   +8 more
semanticscholar   +1 more source

Pulse Pressure, White Matter Hyperintensities, and Cognition: Mediating Effects Across the Adult Lifespan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate whether pulse pressure or mean arterial pressure mediates the relationship between age and white matter hyperintensity load and to examine the mediating effect of white matter hyperintensities on cognition. Methods Demographic information, blood pressure, current medication lists, and Montreal Cognitive Assessment ...
Jade Hannan, Sarah Newman‐Norlund, Natalie Busby, Sarah C. Wilson, Roger Newman‐Norlund, Chris Rorden, Julius Fridriksson, Leonardo Bonilha, Nicholas Riccardi   +8 more
wiley   +1 more source

Bioprinting of Small-Diameter Blood Vessels

Engineering, 2021
There has been an increasing demand for bioengineered blood vessels for utilization in both regenerative medicine and drug screening. However, the availability of a true bioengineered vascular graft remains limited.
Xia Cao, Sushila Maharjan, Ramla Ashfaq, Jane Shin, Yu Shrike Zhang   +4 more
doaj  

Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal.

Journal of Clinical Investigation, 1999
Features that distinguish tumor vasculatures from normal blood vessels are sought to enable the destruction of preformed tumor vessels. We show that blood vessels in both a xenografted tumor and primary human tumors contain a sizable fraction of immature
Laura E. Benjamin, D. Golijanin, A. Itin, D. Pode, E. Keshet   +4 more
semanticscholar   +1 more source

Factors for Rituximab Refractoriness in AQP4‐IgG+ NMOSD: A Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune condition of the central nervous system (CNS), often associated with aquaporin‐4 antibodies (AQP4‐IgG). Rituximab, a CD20+ B‐cell depleting monoclonal antibody, is widely used as first‐line therapy.
Mariano Marrodan, María A. Piedrabuena, María A. Zarate, Sofía Rodríguez Murúa, Ezequiel I. Surace, Mauricio F. Farez, Marcela P. Fiol, María C. Ysrraelit, Jorge Correale   +8 more
wiley   +1 more source