Results 81 to 90 of about 8,434,281 (280)

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu   +7 more
wiley   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Prion diseases are efficiently transmitted by blood transfusion in sheep [PDF]

open access: yes, 2008
The emergence of variant Creutzfeld-Jakob disease, following on from the bovine spongiform encephalopathy (BSE) epidemic, led to concerns about the potential risk of iatrogenic transmission of disease by blood transfusion and the introduction of costly ...
Foster, J.   +8 more
core   +1 more source

Accidental arterial puncture during right internal jugular vein cannulation in cardiac surgical patients

open access: yesAnnals of Cardiac Anaesthesia, 2016
Background: The primary aim of this study was to compare the incidence of accidental arterial puncture during right internal jugular vein (RIJV) cannulation with and without ultrasound guidance (USG).
Madan Mohan Maddali   +5 more
doaj   +1 more source

Segmentation of the Blood Vessels and Optic Disk in Retinal Images

open access: yesIEEE journal of biomedical and health informatics, 2014
Retinal image analysis is increasingly prominent as a nonintrusive diagnosis method in modern ophthalmology. In this paper, we present a novel method to segment blood vessels and optic disk in the fundus retinal images.
Ana G. Salazar-Gonzalez   +3 more
semanticscholar   +1 more source

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin   +11 more
wiley   +1 more source

Lymphatic vascular morphogenesis in development, physiology, and disease [PDF]

open access: yes, 2011
The lymphatic vasculature constitutes a highly specialized part of the vascular system that is essential for the maintenance of interstitial fluid balance, uptake of dietary fat, and immune response. Recently, there has been an increased awareness of the
Amélie Sabine   +6 more
core   +3 more sources

LES of non-newtonian physiological blood flow [PDF]

open access: yes, 2009
Large Eddy Simulation (LES) is performed to study the physiological pulsatile transition to turbulent non-Newtonian blood flow through a 3D model of arterial stenosis using the different non-Newtonian blood viscosity models.
Molla, M.M., Paul, M.C.
core   +4 more sources

Interstitial Cells of Blood Vessels

open access: yesThe Scientific World Journal, 2010
Blood vessels are made up of several distinct cell types. Although it was originally thought that the tunica media of blood vessels was composed of a homogeneous population of fully differentiated smooth muscle cells, more recent data suggest the ...
Vladimír Pucovský
doaj   +1 more source

The Blood Vessels of the Human Skin and Their Responses

open access: yesNature, 1928
SOME time ago a paper was sent to a certain society for publication; the comment made upon it was: “Whoever undertakes to act as referee will have to do a year's solid work before he sends in a report.” The author of the present review feels much in the ...
J. B.
semanticscholar   +1 more source

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