Results 61 to 70 of about 8,434,281 (280)

Significance of Blood Vessels in Optimization of Absorbed Power and Temperature Distributions during Hyperthermia

, 2011
This study investigated the significance of blood vessels in the absorbed power and temperature distributions when optimization was employed during hyperthermia. The treated tumor region was simulated using a three- dimensional (3D) tissue model embedded
HUANG, HUANG-WEN;LIAUH, CHIHNG-TSUNG;SHIH, TZU- CHING;HORNG, TZYY-LENG;LIN, WIN-LI, 黃煌文;廖慶聰;施子卿;洪子倫;林文澧   +1 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Cardiopulmonary Events of the Elderly (≥75 Years) during Clazosentan Therapy after Subarachnoid Hemorrhage: A Retrospective Study from a Tertiary Stroke Center in Japan

Medicina
Clazosentan has been shown to prevent vasospasm and reduce mortality in patients after aneurysmal subarachnoid hemorrhage (SAH) and has been approved for clinical use in Japan; however, its systemic events in the elderly (aged ≥ 75 years) have not been ...
Tatsushi Mutoh, Hiroaki Aono, Wataru Seto, Takehiro Kimoto, Ryota Tochinai, Junta Moroi, Tatsuya Ishikawa   +6 more
doaj   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels

Nature Communications, 2013
Cancer and stromal cells actively exert physical forces (solid stress) to compress tumour blood vessels, thus reducing vascular perfusion. Tumour interstitial matrix also contributes to solid stress, with hyaluronan implicated as the primary matrix ...
Vikash P Chauhan, John D. Martin, Hao Liu, D. Lacorre, Saloni R. Jain, S. V. Kozin, T. Stylianopoulos, A. Mousa, Xiaoxing Han, Pichet Adstamongkonkul, Zoran Popović, Pei-Gen Huang, M. Bawendi, Y. Boucher, R. Jain   +14 more
semanticscholar   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Dual‐energy X‐ray absorptiometry for detecting neurogenic pulmonary edema in a mouse model of subarachnoid hemorrhage

Animal Models and Experimental Medicine
Murine subarachnoid hemorrhage (SAH) induced using the filament perforation method is a useful in vivo experimental model to investigate the pathophysiological mechanisms in the brain underlying SAH.
Tatsushi Mutoh, Hiroaki Aono, Yushi Mutoh, Tatsuya Ishikawa   +3 more
doaj   +1 more source

Diffusion MRI Fiber Tractography and Benzodiazepine SPECT Imaging for Assessing Neural Damage to the Language Centers in an Elderly Patient after Successful Reperfusion Therapy

Geriatrics
Background: Intravenous thrombolysis and mechanical thrombectomy are the first-line reperfusion therapies for acute ischemic stroke. Here, we describe the utility of diffusion magnetic resonance imaging (MRI) fiber tractography and 123I-iomazenil ...
Tatsushi Mutoh, Yasuyuki Yoshida, Yasuko Tatewaki, Hongkun Chin, Ryota Tochinai, Junta Moroi, Tatsuya Ishikawa   +6 more
doaj   +1 more source

Nerves are more abundant than blood vessels in the degenerate human intervertebral disc

Arthritis Research & Therapy, 2015
BackgroundChronic low back pain (LBP) is the most common cause of disability worldwide. New ideas surrounding LBP are emerging that are based on interactions between mechanical, biological and chemical influences on the human IVD.
A. Binch, A. Cole, L. Breakwell, A. Michael, N. Chiverton, L. Creemers, A. Cross, C. L. Le Maitre   +7 more
semanticscholar   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source