Results 81 to 90 of about 2,923,932 (298)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Primary antibodies used for Western blotting analyses.

open access: yes, 2013
Primary antibodies used for Western blotting analyses.
Jean-François Merlin (345501)   +5 more
core   +1 more source

List of primary antibodies used for Western blotting.

open access: yes, 2023
List of primary antibodies used for Western blotting.
Danting Zhu (7056017)   +8 more
core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Western Blotting and Immunoprecipitation of Native Human PIEZO1 Channels

open access: yesBio-Protocol
PIEZO1 is a mechanically activated ion channel essential for mechanotransduction and downstream signaling in almost all organ systems. Western blotting is commonly used to study the expression, stability, and post-translational modifications of proteins.
Jinyuan Vero Li   +2 more
doaj   +1 more source

Antibodies used for Western blotting and Immunohistochemistry.

open access: yes, 2016
Antibodies used for Western blotting and Immunohistochemistry.
Paula de Carvalho Papa (3203193)   +4 more
core   +1 more source

western blotting data.xls

open access: yes, 2020
The expression of MDA5, MAVS, IFN regulatory factor 7, and IFN-stimulated gene 15 in the skeletal muscles of DM patients was studied using western blotting in the skeletal muscles of four patients and four normal healthy ...
Yanyan Jiang (8456151)
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

List of antibodies used for Western blotting.

open access: yes, 2019
List of antibodies used for Western blotting.
Mohamed Ali Marey (3135117)   +11 more
core   +1 more source

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