Results 141 to 150 of about 54,144 (209)

AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective

Advanced Intelligent Discovery, EarlyView.
The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley   +1 more source

Sharper displays via field control. [PDF]

Light Sci Appl
Ma Y.
europepmc   +1 more source

Microrobotic Catheterization of the Ophthalmic Artery for Targeted Treatment of Retinoblastoma

Advanced Intelligent Systems, EarlyView.
A microrobotic platform is presented that allows teleoperated and autonomous navigation of flow‐driven magnetic microcatheters, MagFlow, into the ophthalmic artery for superselective intra‐arterial infusion of chemotherapy to treat retinoblastoma. Extensive benchtop validations with patient‐derived biomimetic phantoms under optical and fluoroscopic ...
Artur Banach, Mehdi Krichen, Julian Raub, Christina Stathopoulos, Bruno Bartolini, Mahmut Selman Sakar   +5 more
wiley   +1 more source

Allosteric Regulation of Photophysics and Binding in Oxazine‐macrocycle Complexes at Single‐molecule Resolution

Angewandte Chemie, EarlyView.
This work explores the interactions between the oxazine dye ATTO655 and two macrocyclic hosts using optical (single‑molecule) spectroscopy. Although ATTO655 forms a classical inclusion complex with cucurbit[8]uril (CB8), its interaction with p‑sulfonatocalix[4]arene (sCX4) leads to the formation of dim exclusion complexes.
Siyu Lu, Thomas‐Otavio Peulen, Hongbin Wu, Florian Lindemann, Despoina Kapiki, Rasmus Linser, Andreas Hennig, Thorben Cordes   +7 more
wiley   +2 more sources

The Templating Software Spectrum: Unveiling Variations in the 3D Assessment of Glenoid Morphology in Shoulder Arthroplasty Planning. [PDF]

Cureus
Matheron G, Ong J, Rumian A, Assiotis A, Uppal HS.   +4 more
europepmc   +1 more source

OntoLogX: Ontology‐Guided Knowledge Graph Extraction From Cybersecurity Logs With Large Language Models

Advanced Intelligent Systems, EarlyView.
OntoLogX is an autonomous AI agent that uses large language models to transform unstructured cyber security logs into ontology grounded knowledge graphs. By integrating retrieval augmented generation, iterative correction, and a light‐weight log ontology, OntoLogX produces semantically consistent intelligence that links raw log events to MITRE ATT & CK
Luca Cotti, Idilio Drago, Anisa Rula, Devis Bianchini, Federico Cerutti   +4 more
wiley   +1 more source

Bifurcation of *COOH Pathway Determines HCOOH Formation in CO2 Electroreduction on Bismuth

Angewandte Chemie, EarlyView.
Driven by the mechanistic debate of Bi‐catalyzed CO2‐to‐HCOOH conversion, ambiguity remains regarding true reaction pathways. To resolve this, we combined constant‐potential AIMD simulations with spectroscopic evidence to analyze the competitive pathways.
Hyun Dong Jung, Jiawei Deng, Yanbo Hua, Kun Jiang, Seoin Back   +4 more
wiley   +2 more sources

Diagnosis of pediatric mitochondrial diseases via targeted next-generation sequencing (NGS): real-world data with the Blueprint Genetics^® platform. [PDF]

Orphanet J Rare Dis
Sapuppo A, Privitera GF, Sortino V, Pavone P, Polizzi A, Ruggieri M, Falsaperla R.   +6 more
europepmc   +1 more source

Light‐Controlled Modulation of 15‐Lipoxygenase‐1 Regulates Intestinal Inflammatory Signaling

Angewandte Chemie, EarlyView.
The developed target‐guided strategy enables the rational design of diazo‐based photoswitchable inhibitors of 15‐lipoxygenase‐1. Distinct molecular architectures program opposite light‐dependent activity, allowing on‐demand control of enzyme inhibition.
Anastasia Louka, Eirini‐Eleni Kalaitzaki, Athanasios Panousis, Sotirios Bonoras, Charalampos Livas, George Froudakis, Ioannis Drygiannakis, Athina Damianaki, George Kolios, Vassilis Valatas, Nikolaos Eleftheriadis   +10 more
wiley   +2 more sources

Uncovering the electrical synapse proteome in retinal neurons via in vivo proximity labeling. [PDF]

Elife
Tetenborg S, Shihabeddin E, Kumar EOAM, Sigulinsky CL, Dedek K, Lin YP, Echeverry FA, Hoff H, Pereda AE, Jones BW, Ribelayga CP, Ebnet K, Matsuura K, O'Brien J.   +13 more
europepmc   +1 more source