Results 181 to 190 of about 54,565 (260)

Pharmacological PIK3C2B inhibition rescues XLMTM phenotype in mouse models and identifies molecular markers of disease. [PDF]

JCI Insight
Shearer A, Brooks ML, Chen MM, Samarakoon T, Hsieh J, Kondakci G, Perola E, Brubaker J, Fetalvero K, Schalm S, Caetano-Lopes J.   +10 more
europepmc   +1 more source

Direct Solar Power‐Driven Durable Ammonia Electrosynthesis From Nitrate Under Fluctuating Voltage Conditions

Angewandte Chemie, EarlyView.
Isolated Sn sites on Cu(111) induce a highly asymmetric charge distribution, which promotes water dissociation, accelerates key intermediate hydrogenation, and suppresses competing hydrogen evolution. As a result, SnCu111 delivers NH3 Faradaic efficiencies above 90% over an 800 mV potential window and enables stable direct solar power‐driven NH3 ...
Xiaokang Wang, Jiankun Li, Liyun Wu, Sirui Tang, Chuangwei Liu, Jianping Yang, Qilong Wu, Xiangdong Yao, Jun Chen   +8 more
wiley   +1 more source

Developing a persona-driven, mHealth-enabled care model for young men with hypogonadism: a methods-based approach to early risk stratification and prevention. [PDF]

Front Reprod Health
Garifalos F, Menafra D, de Angelis C, Larocca A, Virgolesi M, Aprano S, De Luca V, Rea T, Attaianese E, Perillo M, Lemmo D, Freda MF, Iaccarino G, Illario M, Colao A, Pivonello R.   +15 more
europepmc   +1 more source

Light‐Controlled Modulation of 15‐Lipoxygenase‐1 Regulates Intestinal Inflammatory Signaling

Angewandte Chemie, EarlyView.
The developed target‐guided strategy enables the rational design of diazo‐based photoswitchable inhibitors of 15‐lipoxygenase‐1. Distinct molecular architectures program opposite light‐dependent activity, allowing on‐demand control of enzyme inhibition.
Anastasia Louka, Eirini‐Eleni Kalaitzaki, Athanasios Panousis, Sotirios Bonoras, Charalampos Livas, George Froudakis, Ioannis Drygiannakis, Athina Damianaki, George Kolios, Vassilis Valatas, Nikolaos Eleftheriadis   +10 more
wiley   +1 more source

Phenotypic Heterogeneity in Titinopathies with Peripheral Nerve Involvement in Pediatric Age: Two Case Reports. [PDF]

J Clin Med
Cesaroni CA, Pisanò G, Marton M, Caraffi SG, Rizzi S, Pantani A, Ziveri D, Pollazzon M, Koskenvuo J, Frattini D, Fusco C.   +10 more
europepmc   +1 more source

Molecular Engineering Boosts Photon‐Activated Immunotherapy for Prostate Cancer Through Concurrent Pyroptosis and cGAS‐STING Pathway Activation

Angewandte Chemie, EarlyView.
The engineered DTSe‐based photosensitizer, DZTSe, emerges as an avant‐garde molecular entity, which can distribute to both the endoplasmic reticulum and mitochondria to concurrently trigger pyroptosis and activate the cGAS‐STING pathway. This dual‐action strategy effectively reprograms the tumor microenvironment, enabling potent eradication of primary ...
Cheng Zhang, Xiaolan Yin, Jeongyeon Hong, Qixian Chen, Weijie Chi, Jingyun Wang, Juyoung Yoon, Haidong Li   +7 more
wiley   +1 more source

A blueprint for integrating nursing informatics into undergraduate nursing programs: A multiple-case study in Australia and South Africa. [PDF]

Int J Nurs Sci
Harerimana A, Wicking K, Biedermann N, Yates K.   +3 more
europepmc   +1 more source

Light‐Driven Out‐of‐Equilibrium Helicity Control in a Diarylethene–Helicene Photosystem

Angewandte Chemie, EarlyView.
Distinct energy landscapes of different helicities in the open and closed states of a diarylethene–helicene photoswitch enable a light‐driven energy ratchet. Helix inversion occurs selectively in the closed form, and the resulting helicity is transferred and kinetically trapped upon ring opening, generating a persistent out‐of‐equilibrium chiral state ...
Eric Sidler, Jinghao Wang, Christina Vallina, Ben L. Feringa   +3 more
wiley   +1 more source

TiO₂ nanolayer-assisted top-interface engineering for disturbance-free FeFETs: a blueprint for future van der Waals memory. [PDF]

Nano Converg
Kang H, Kwak J, Kim G, Lee S, Kim Y, Park S, Lim S, Seo K, Kim W, Ha D, Ahn J, Jeon S.   +11 more
europepmc   +1 more source

Microenvironmental Tuning in Isostructural Conjugated Metal–Organic Frameworks for Superior Photocatalytic H2O2 Generation

Angewandte Chemie, EarlyView.
Two isostructural conjugated‐MOFs (Fe‐Tp and Mn‐Tp) photocatalysts were engineered with nonequivalent microenvironmental redox tuning for hydrogen peroxide production. The manganese analog engages both the oxygen reduction reaction and the water oxidation reaction while suppressing decomposition, delivering 10 487 µmol g−1 h−1 with an apparent quantum ...
Kayaramkodath Chandran Ranjeesh, Avanti Chakraborty, Pilar Pena Sánchez, Jose Ignacio Martinez, Abdul Khayum Mohammed, Nada Elmerhi, Stefano Canossa, Matjaž Finšgar, Felipe Gándara, Pradip Pachfule, Dinesh Shetty   +10 more
wiley   +1 more source