Results 81 to 90 of about 257,128 (312)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Variações da melancolia na música do século XX:

open access: yesArtefilosofia, 2017
O presente texto se debruça sobre três figuras icônicas da música “melancólica” do século XX: a cantora de blues Bessie Smith, a cantora de jazz Billie Holiday e o trompetista Miles Davis.
Rainer Patriota
doaj  

Blue acid blues [PDF]

open access: yesNephrology Dialysis Transplantation, 2004
Tilman, Dreykluft   +5 more
openaire   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

The Whalesong [PDF]

open access: yes, 2006
Agreement reached on gas line, oil tax -- Opinions on Planned Parenthood's arrival are varied -- An inspiring look out the window -- Campus calendar -- UAS rolls out new digital music service -- The realities of limited government -- Foreign oil ...

core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Jazz Lab Ensembles Concert, December 9, 1993 [PDF]

open access: yes, 1993
This is the concert program of the Jazz Lab Ensembles Concert performance on Thursday, December 9, 1993 at 8:00 p.m., at the Concert Hall, 855 Commonwealth Avenue. Works performed were Concerto for Piano and Jazz Combo, Op.
School of Music, Boston University
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

“The Noise of Our Living”: Richard Wright and Chicago Blues

open access: yesHumanities
Historicizing the musical genre known as “Chicago blues,” I further complicate Richard Wright’s already complicated attitudes toward “the folk” and modernity.
Jeff Wimble
doaj   +1 more source

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