Results 141 to 150 of about 286,241 (363)

The use of areal surface topography analysis for the inspection of micro-fabricated thin foil laser targets for ion acceleration

open access: yes, 2012
This paper proposes a novel approach to the characterization of critical dimensions and geometric form error at micro and sub-micrometric scales, suitable for application to micro-fabricated parts and devices. Thin foil laser targets for ion acceleration
Senin N   +7 more
core   +1 more source

Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun   +27 more
wiley   +1 more source

The value of play for conflict management: a case study

open access: yesSouth African Journal of Education, 2009
This is a case study of a conflict management intervention in two secondary schools in post-apartheid South Africa. The feature of the intervention that we examine is the use of play as an educational strategy.
Lyn Snodgrass, Richard Blunt
doaj  

EEPD1 Inhibition Unleashes Antitumor Immunity in Colorectal Cancer by Activating the cGAS‐STING Pathway

open access: yesAdvanced Science, EarlyView.
In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo   +8 more
wiley   +1 more source

Letter from Br. Gen. Blunt to Lt. Col. Hardinge, Mafra, August 25, 1811

open access: yes
Letter written by Brigadier General Richard Blunt to Lieutenant Colonel Henry Hardinge on August 25, 1811, while in Mafra, Portugal.This material is part of a larger collection, for which there is a guide on-line at: http://www.lib.utexas.edu/taro ...
Blunt, Richard
core  

SAA/FPR2 Signaling Between Pericentral Hepatocytes and Macrophages Exacerbates Zonated Liver Transplant Injury

open access: yesAdvanced Science, EarlyView.
After liver transplantation, ischemia‐reperfusion injury is more severe in pericentral regions. Multiomic analyses of human grafts and mouse models identify FOXO1 activation in pericentral hepatocytes as an upstream driver of SAA secretion. SAA recruits and activates FPR2+ macrophages, amplifying local inflammation. Amilo‐5MER inhibits SAA bioactivity,
Feng Zhang   +19 more
wiley   +1 more source

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

open access: yesAdvanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao   +28 more
wiley   +1 more source

A voyage into the Levant : A brief Relation of a Journey lately performed by Mr. Henry Blunt Gentleman, from England by the way of Venice, into Dalmatia, Sclavonia, Bosna, Hungary, Macedonia, Thessaly, Thrace, Rhodes and Egypt, unto Gran Cairo : with part

open access: yes, 2009
Dedication:Pagination: 228PVolumes: 1Edition:4thText Genre ...
Traveller-Blount, Henry-Blunt Henry   +7 more
core  

Home - About - Disclaimer - Privacy