Results 121 to 130 of about 544,641 (311)

An investigation of some effects of mach number and air temperature on the hypersonic flow over a blunt body [PDF]

Mach number and air temperature effect on hypersonic flow over blunt ...
Seiff, A., Sommer, S. C.
core   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

A direct method for calculation of the flow about an axisymmetric blunt body at angle of attack [PDF]

Direct calculation method for supersonic inviscid flow around axisymmetric blunt body with conically reentrant afterbody flying at large angle of ...
Bohachevsky, I. O., Mates, R. E.
core   +1 more source

Filling the Void: A Low Cost, High-Yield Method to Addressing Incidental Findings in Trauma Patients [PDF]

, 2017
In this study we: Report the incidence of incidental findings in a suburban trauma center treating primarily blunt and elderly trauma Propose simple solutions to increase the rate of disclosure to patientshttps://jdc.jefferson.edu/patientsafetyposters ...
Alswealmeen, W., Bertozzi, D., Gartner, L., Kirton, O., Lim, P., Rogers, A., Sabapathi, P., Shadis, R., Sich, N., Sternlieb, J., Yuschak, J.   +10 more
core   +1 more source

Promotion of DFU Wound Healing via BRG1–COL16A1 Axis in Fibroblasts

Advanced Science, EarlyView.
In normal wound healing, transcription factor BRG1 is upregulated and binds the COL16A1 promoter to enhance its expression, promoting fibroblast proliferation, migration, contraction, extracellular matrix deposition, and granulation tissue formation, thus accelerating wound closure.
Penghui Wang, Jiaming Sun, Ying Wang, Bichen Ren, Yuxin Liu, Yunhan Liu, Liang Chen, Lu Yu, Tao Dai, Li Yu, Zhihui Dong   +10 more
wiley   +1 more source

Hypersonic blunt-body flow of a radiating gas at low density [PDF]

Hypersonic blunt body flow of radiating gas at low ...
Schneider, W. A.
core   +1 more source

Mitochondrial CircRNA CircMT‐RNR2 Safeguards Antioxidant Defense to Support Fibroblast Functions in Wound Repair

Advanced Science, EarlyView.
CircMT‐RNR2 promotes wound healing by enhancing fibroblast proliferation, migration, contraction, and extracellular matrix (ECM) production. It sustains mitochondrial redox balance by stabilizing the antioxidant protein PRDX3, thereby reducing ROS‐induced damage. In diabetic foot ulcers, hypoxia, hyperglycemia, and reduced FGF2 and EGF expression lower
Guanglin Niu, Jennifer Geara, Yongjian Chen, Lihua Luo, Yanwei Xiao, Zhuang Liu, Margaux Gaborieau, Ling Pan, Edmund Loh, Dongqing Li, Pehr Sommar, Aoxue Wang, Xiaowei Zheng, Ning Xu Landén   +13 more
wiley   +1 more source

The value of play for conflict management: a case study

South African Journal of Education, 2009
This is a case study of a conflict management intervention in two secondary schools in post-apartheid South Africa. The feature of the intervention that we examine is the use of play as an educational strategy.
Lyn Snodgrass, Richard Blunt
doaj  

Measurements of an ionizable constituent of low ionosphere using a Lyman-alpha source and blunt probe [PDF]

Ionizable constituent density measurement of D region using Lyman-alpha source and blunt ...
Hale, L. C., Pontano, B. A.
core   +1 more source

Beyond CD30: Dual‐Targeting of Malignant and Regulatory T Cells by Brentuximab Vedotin Remodels the Lymphoma Microenvironment and Overcomes Resistance via BCL2 Inhibition in Mycosis Fungoides

Advanced Science, EarlyView.
Single‐cell RNA analyses of paired lesions from CD30+ mycosis fungoides patients demonstrate that brentuximab vedotin (BV) induces immunogenic cell death in both CD30+ and CD30− malignant T cells. BV also targets regulatory T cells and remodels tumor microenvironment, while resistance is driven by impaired IFN responses, drug efflux, and BCL2 ...
Yi Jiang, Pan Lai, Mingjia Li, Yujie Wen, Mengzhou Cao, Yu Xiao, Zhuojing Chen, Jingru Sun, Yang Wang   +8 more
wiley   +1 more source