Results 151 to 160 of about 578,151 (361)

Nurr1 Orchestrates Claustrum Development and Functionality

open access: yesAdvanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan   +12 more
wiley   +1 more source

An investigation of some effects of mach number and air temperature on the hypersonic flow over a blunt body [PDF]

open access: yes
Mach number and air temperature effect on hypersonic flow over blunt ...
Seiff, A., Sommer, S. C.
core   +1 more source

Ventricular septal defect, developed due to the coronary artery injury after blunt chest trauma in childhood

open access: bronze, 2012
Zehra Karataş   +5 more
openalex   +1 more source

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

open access: yesAdvanced Science, EarlyView.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang   +18 more
wiley   +1 more source

Measurements of an ionizable constituent of low ionosphere using a Lyman-alpha source and blunt probe [PDF]

open access: yes
Ionizable constituent density measurement of D region using Lyman-alpha source and blunt ...
Hale, L. C., Pontano, B. A.
core   +1 more source

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

open access: yesAdvanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang   +9 more
wiley   +1 more source

Injuries Caused By Blunt Trauma ; A Case Report

open access: diamond, 2023
Yocky Andre Siahaan   +2 more
openalex   +2 more sources

Allelic Variation in Maize Malate Dehydrogenase 7 Shapes Promoter Methylation and Banded Leaf and Sheath Blight Resistance

open access: yesAdvanced Science, EarlyView.
In this study maize chloroplastic malate dehydrogenase7 (ZmMDH7), is identified as a Rhizoctonia solani resistance gene in maize. ZmMDH7 is regulated by transcription factor ZmWRKY44 via pathogens challenge to elevate mitochondrial ROS and SA signaling pathway.
Luyang Wei   +9 more
wiley   +1 more source

Flow field computations for blunt bodies in planetary environments /equilibrium/ Final report [PDF]

open access: yes
Radiative and convective heat transfer about two blunt bodies traveling at hypersonic speeds at zero angle of attack in assumed Mars atmosphere of nitrogen and carbon ...
Dohner, C. V.   +3 more
core   +1 more source

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