Visualizing bovine leukemia virus (BLV)-infected cells and measuring BLV proviral loads in the milk of BLV seropositive dams [PDF]
Bovine leukemia virus (BLV) infects cattle and causes serious problems for the cattle industry, worldwide. Vertical transmission of BLV occurs via in utero infection and ingestion of infected milk and colostrum.
Sonoko Watanuki +9 more
doaj +5 more sources
Experimental infection of sheep with bovine leukemia virus (BLV): minimum dose of BLV-FLK cells and cell-free BLV and neutralization activity of natural antibodies = Infección experimental en ovinos con el virus de leucosis bovina: dosis mínima de células BLV-FLK y virus libre de células, y actividad neutralizante de anticuerpos naturales [PDF]
Bovine leukemia virus (BLV) is an important cattle pathogen that causes major economic losses worldwide, especially in dairy farms. The use of animal models provides valuable insight into the pathogenesis of viral infections.
Porta, Natalia Gabriela +7 more
core +5 more sources
BLV-CoCoMo-qPCR: a useful tool for evaluating bovine leukemia virus infection status [PDF]
Background Bovine leukemia virus (BLV) is associated with enzootic bovine leukosis, which is the most common neoplastic disease of cattle. BLV infects cattle worldwide, imposing a severe economic impact on the dairy cattle industry.
Jimba Mayuko +8 more
doaj +2 more sources
The complete genomic sequence of an in vivo low replicating BLV strain [PDF]
DNA was extracted from lamb lymphocytes that were infected in vivo with a BLV strain after inoculation with the peripheral blood mononuclear cells from a persistently sero-indeterminate, low viral load, BLV-infected Holstein cow (No.
Ceriani Carolina +9 more
doaj +2 more sources
Activation of BLV Transcription by NF-κB and Tax
Bovine leukemia virus (BLV) is the causative agent of bovine leukosis, a naturally occurring fatal disease in cattle. BLV transcription is regulated by cellular transcription factors and the virally encoded oncoprotein Tax.
Nyborg, Jennifer K +2 more
core +3 more sources
Stage-Dependent Transcriptional Reprogramming of B-Cell Receptor Signaling and Antigen Presentation During Bovine Leukemia Virus-Driven Lymphomagenesis. [PDF]
ABSTRACT Bovine leukemia virus (BLV), an oncogenic deltaretrovirus, establishes lifelong infection in cattle and induces enzootic bovine leukosis in a subset of animals following prolonged latency. Despite extensive evidence of immune dysregulation, stage‐specific transcriptional reprogramming of B cells, the primary viral reservoir remains ...
Akbarin MM +6 more
europepmc +2 more sources
Evaluation of bovine leukaemia virus infection control measures in Japanese Black beef cattle breeding farms: A 7-year longitudinal study based on proviral load. [PDF]
Abstract Background Bovine leukaemia virus (BLV) infection remains a major problem for Japanese Black (Wagyu) cattle, and effective and sustainable control measures are essential to prevent its spread in breeding herds. This study aimed to monitor the BLV infection status of all cattle at a Japanese Black breeding farm in Kagoshima Prefecture, Japan ...
Kajisa M +9 more
europepmc +2 more sources
Bovine leukaemia virus (BLV), which is classified as a Deltaretrovirus, is the aetiologic agent of enzootic bovine leukosis (EBL), a chronic lymphoproliferative disorder with a worldwide distribution.
Yi-Chen Chen +4 more
doaj +1 more source
BLV: lessons on vaccine development [PDF]
Abstract Vaccination against retroviruses is a challenge because of their ability to stably integrate into the host genome, undergo long-term latency in a proportion of infected cells and thereby escape immune response. Since clearance of the virus is almost impossible once infection is established, the primary goal is to achieve ...
Alejandro Abdala +20 more
openaire +5 more sources
Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leukosis (EBL), a malignant B cell lymphoma. However, the mechanisms of BLV-associated lymphomagenesis remain poorly understood.
Chihiro Ochiai +14 more
doaj +1 more source

