Results 71 to 80 of about 1,686 (163)

A systematic review of the concept and clinical applications of bone marrow aspirate concentrate in tendon pathology

SICOT-J, 2017
Tendon pathologies are a group of musculoskeletal conditions frequently seen in clinical practice. They can be broadly classified into traumatic, degenerative and overuse-related tendinopathies.
Imam Mohamed A., Holton James, Horriat Saman, Negida Ahmed S., Grubhofer Florian, Gupta Rohit, Narvani Ali, Snow Martyn   +7 more
doaj   +1 more source

Safety of autologous bone marrow aspiration concentrate transplantation: initial experiences in 101 patients

Orthopedic Reviews, 2009
The clinical application of cellular based therapies with ex vivo cultivation for the treatment of diseases of the musculoskeletal system has until now been limited. In particular, the advanced laboratory and technical effort necessary, regulatory issues
Christian Hendrich, Franz Engelmaier, Gerhart Waertel, Rolf Krebs, Marcus Jäger   +4 more
doaj   +1 more source

Side‐to‐side characterisation of cellular content, soluble factors and in vitro potential on chondrocytes for bone marrow aspirate concentrate and adipose‐derived stromal vascular fraction

Journal of Experimental Orthopaedics
Purpose Orthobiologics gained popularity for the treatment of musculoskeletal pathologies, including osteoarthritis (OA). Bone marrow aspirate concentrate (BMAC) and adipose‐derived stromal vascular fraction (SVF) were reported to reduce OA symptoms ...
Enrico Ragni, Michela Taiana, Caterina Visconte, Elizaveta Kon, Simona Landoni, Cecilia Colombo, Laura Mangiavini, Giuseppe Peretti, Laura deGirolamo   +8 more
doaj   +1 more source

Neither Bone Marrow Aspirate Concentrate nor Platelet-Rich Plasma Improves Patient-Reported Outcomes After Surgical Management of Acetabular Labral Tears; However, Bone Marrow Aspirate Concentrate May Be Effective for Moderate Cartilage Damage: A Systematic Review

Arthroscopy, Sports Medicine, and Rehabilitation
Purpose: To (1) systematically assess which orthobiologic agents are being used in acetabular labral repairs and (2) report all available outcomes for patients undergoing operative management for labral repairs with orthobiologic agents.
Bilal S. Siddiq, B.S., Riccardo Giorgino, M.D., Stephen M. Gillinov, A.B., Jonathan S. Lee, B.A., Kieran S. Dowley, B.A., Nathan J. Cherian, M.D., Scott D. Martin, M.D.   +6 more
doaj   +1 more source

Regenerative therapies for femoral head necrosis in the past two decades: a systematic review and network meta-analysis

Stem Cell Research & Therapy
Background Regenerative techniques combined with core decompression (CD) are commonly used to treat osteonecrosis of the femoral head (ONFH). However, no consensus exists on regeneration therapy combined with CD that performs optimally.
Xiaole Wang, Liyou Hu, Bo Wei, Jian Wang, Decai Hou, Xiaolei Deng   +5 more
doaj   +1 more source

Local delivery of TGF-β1-mRNA decreases fibrosis in osteochondral defects

Bioactive Materials
Osteoarthritis (OA) is a condition that affects the quality of life of millions of patients worldwide. Current clinical treatments, in most cases, lead to cartilage repair with deposition of fibrocartilage tissue, which is mechanically inferior and not ...
Gianluca Fontana, Brett Nemke, Yan Lu, Connie Chamberlain, Jae-Sung Lee, Joshua A. Choe, Hongli Jiao, Michael Nelson, Margot Amitrano, Wan-Ju Li, Mark Markel, William L. Murphy   +11 more
doaj   +1 more source

Decreasing Postoperative Narcotic Utilization with the Use of Concentrated Bone Marrow Aspirate in First Metatarsophalangeal Joint Interposition Arthroplasty

Foot & Ankle Orthopaedics, 2018
Category: Midfoot/Forefoot Introduction/Purpose: Interposition arthroplasty is an interim procedure for the treatment of first metatarsophalangeal osteoarthritis demonstrating excellent survivorship. The procedure is commonly performed at our institution
Camilla Maccario MD, Michael Aynardi MD, Eric Tan MD, Lew Schon MD   +3 more
doaj   +1 more source

Bone Marrow Aspirate Concentrate Combined with Ultra-Purified Alginate Bioresorbable Gel Enhances Intervertebral Disc Repair in a Canine Model: A Preclinical Proof-of-Concept Study

Cells
Although discectomy is commonly performed for lumbar intervertebral disc (IVD) herniation, the capacity for tissue repair after surgery is limited, resulting in residual lower back pain, recurrence of IVD herniation, and progression of IVD degeneration ...
Daisuke Ukeba, Yoko Ishikawa, Katsuhisa Yamada, Takashi Ohnishi, Hiroyuki Tachi, Khin Khin Tha, Norimasa Iwasaki, Hideki Sudo   +7 more
doaj   +1 more source

A New Approach to Postoperative Rehabilitation following Mosaicplasty and Bone Marrow Aspiration Concentrate (BMAC) Augmentation

Biomedicines
Background: Chondral defects in the knee present a significant challenge due to their limited self-healing capacity, often leading to joint degeneration and functional disability. Current treatments, including surgical approaches like mosaicplasty and regenerative therapies such as bone marrow aspirate concentrate (BMAC) augmentation, aim to address ...
Robert Gherghel, Ilie Onu, Daniel Iordan, Bogdan Antohe, Ioana-Irina Rezus, Ovidiu Alexa, Luana Macovei, Elena Rezus   +7 more
openaire   +3 more sources

Acute Back Pain After Intradiscal BMAC: A Case Report

Interventional Pain Medicine, 2023
Ajay K. Patel, Zachary Danssaert, Jaspal R. Singh   +2 more
openaire   +1 more source