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Importinα3 Mediates BmNPV Nucleocapsid Nuclear Entry via a Ran-Independent Pathway

Current Microbiology
Tianran Zhang   +5 more
semanticscholar   +2 more sources

Quantitative proteomics of Bombyx mori after BmNPV challenge

Journal of Proteomics, 2018
The domesticated silkworm is an ideal and economic insect model that plays crucial roles in sericulture and bioreactor. Bombyx mori nucleopolyhedrovirus (BmNPV) is not only an infectious pathogen to B. mori, but also an efficient vector expressing recombinant proteins.
Fuxiang Mao   +6 more
openaire   +2 more sources

Over expression of bmo-miR-2819 suppresses BmNPV replication by regulating the BmNPV ie-1 gene in Bombyx mori

Molecular Immunology, 2019
Bombyx mori nucleopolyhedrovirus (BmNPV) is a major pathogen that threatens the growth and sustainability of the sericulture industry. Accumulating studies in recent years suggest that insect viruses infection can change the host microRNAs (miRNAs) expression profile and both cellular and viral miRNAs play roles in host-pathogen interactions. Until now,
Ping, Wu   +7 more
openaire   +2 more sources

bmnpv-miR-3 facilitates BmNPV infection by modulating the expression of viral P6.9 and other late genes in Bombyx mori

Insect Biochemistry and Molecular Biology, 2014
During the last decade, microRNAs (miRNAs) have emerged as fine tuners of gene expression in various biological processes including host-pathogen interactions. Apart from the role of host encoded miRNAs in host-virus interactions, recent studies have also indicated the key role of virus-encoded miRNAs in the regulation of host defense responses. In the
C P, Singh, J, Singh, J, Nagaraju
openaire   +2 more sources

BmNPV-induced hormone metabolic disorder in silkworm leads to enhanced locomotory behavior

Developmental & Comparative Immunology, 2021
Many parasites alter the host locomotory behaviors in a way that increases their fitness and progeny transmission. Baculoviruses can manipulate host physiology and alter the locomotory behavior by inducing 'hyperactivity' (increased locomotion) or 'tree-top disease' (climbing high up to the top before dying).
Yang Li   +3 more
openaire   +2 more sources

Bombyx mori PAT4 gene inhibits BmNPV infection and replication through autophagy.

Journal of Invertebrate Pathology
Proton-assisted amino acid transporter 4 (PAT4) is a member of the solute carrier (SLC) 36 family, which mediates the transmembrane transport of amino acids and their derivatives. However, the function of PAT4 in Bombyx mori is not clear. In this study, BmPAT4 was cloned and identified using PCR technology.
Kaifang Jia   +10 more
semanticscholar   +3 more sources

Nup358 and Nup153 Facilitate nuclear import of BmNPV nucleocapsids in Bombyx mori cells.

Journal of Invertebrate Pathology
Nuclear pore complexes (NPCs) are crucial for the nuclear import of viral genomes, serving as gateways for many viruses to deliver their genetic material into host cell nuclei. However, the role of NPCs in the entry of Bombyx mori nucleopolyhedrovirus (BmNPV) remains poorly understood. This study investigates the involvement of specific nucleoporins in
Kangping Yin   +3 more
semanticscholar   +3 more sources

Identification of key metabolic pathways reprogrammed by BmNPV in silkworm Bombyx mori

Journal of Invertebrate Pathology, 2022
Elucidating the mechanism of infection of Bombyx mori nuclear polyhedrosis virus (BmNPV) and host antiviral response remains a major scientific task in sericulture. Virus invasion causes a series of antiviral immune responses in the host, and successful infection leads to massive changes in the host's physiological and biochemical state.
Weiwei, Zhou   +8 more
openaire   +2 more sources

BmADARa cooperatively inhibits BmNPV proliferation through the interaction of its dsRBD2 with BmDcr-2-DEXHc in silkworm, Bombyx mori.

Insect Science
Adenosine deaminases that act on RNA (ADARs) are RNA editing enzymes capable of converting adenosine into inosine at specific sites within double-stranded RNA (dsRNA), widely distributed across various animal species.
Song Jiang   +9 more
semanticscholar   +1 more source

Bombyx mori cell division cycle protein 37 promotes the proliferation of BmNPV

Pesticide Biochemistry and Physiology, 2021
Cell division cycle protein 37 (Cdc37) is a molecular chaperone that actively participates in many intracellular physiological and biochemical processes as well as pathogen infection. However, the function of Cdc37 in silkworm cells under Bombyx mori nucleopolyhedrovirus (BmNPV) infection is unknown.
Qian, Zhang   +6 more
openaire   +2 more sources

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