Results 251 to 260 of about 148,190 (307)
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Orthopaedic Nursing, 2005
Bone morphogenetic proteins (BMP) are being increasingly used in orthopaedic surgery. These small molecules are capable of inducing bone formation when delivered in the appropriate concentration and on the appropriate scaffold. Not all BMPs are equally effective, and there are currently only two Food and Drug Administration (FDA)-approved "on-label ...
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Bone morphogenetic proteins (BMP) are being increasingly used in orthopaedic surgery. These small molecules are capable of inducing bone formation when delivered in the appropriate concentration and on the appropriate scaffold. Not all BMPs are equally effective, and there are currently only two Food and Drug Administration (FDA)-approved "on-label ...
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To BMP or not to BMP during vertebrate limb bud development
Seminars in Cell & Developmental Biology, 2014The analysis of vertebrate limb bud development provides insight of general relevance into the signaling networks that underlie the controlled proliferative expansion of large populations of mesenchymal progenitors, cell fate determination and initiation of differentiation.
Pignatti, Emanuele +2 more
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Molecular recognition of BMP-2 and BMP receptor IA
Nature Structural & Molecular Biology, 2004Bone morphogenetic protein-2 (BMP-2) and other members of the TGF-beta superfamily regulate the development, maintenance and regeneration of tissues and organs. Binding epitopes for these extracellular signaling proteins have been defined, but hot spots specifying binding affinity and specificity have so far not been identified.
Keller, Sascha +4 more
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Proceedings of the 5th EAI International Conference on Smart Objects and Technologies for Social Good, 2019
In this paper, we introduce a new communication protocol for machine to machine communication within the Internet of Things (IoT) based on physical distances rather than on addresses. A common challenge with the IoT is to filter the quantity of data that can be collected, especially in centralized solutions.
Frédéric Bergéron +3 more
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In this paper, we introduce a new communication protocol for machine to machine communication within the Internet of Things (IoT) based on physical distances rather than on addresses. A common challenge with the IoT is to filter the quantity of data that can be collected, especially in centralized solutions.
Frédéric Bergéron +3 more
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Injury, 2005
Bone morphogenetic proteins (BMPs) are polypeptides discovered by Marshall Urist in 1965 and later defined by his co-workers as multifunctional cytokines involved in osteoinduction. They are members of the transforming growth factor-beta superfamily with the exception of the BMP-1.
De Biase, Pietro, Capanna, Rodolfo
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Bone morphogenetic proteins (BMPs) are polypeptides discovered by Marshall Urist in 1965 and later defined by his co-workers as multifunctional cytokines involved in osteoinduction. They are members of the transforming growth factor-beta superfamily with the exception of the BMP-1.
De Biase, Pietro, Capanna, Rodolfo
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Discovery and development of BMPs
Injury, 2005In the early 1970s, the isolation and identification of bone morphogenetic proteins (BMPs) was a major breakthrough for the understanding of the distinct biological events occurring during bone formation. Not surprising, since their discovery, BMPs have been perhaps one of the most intensively studied group of factors in various physiological processes.
Rozalia, Dimitriou, Peter V, Giannoudis
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BMP Signaling and Skeletogenesis
Annals of the New York Academy of Sciences, 2006Abstract: Bone morphogenetic proteins (BMPs) are members of the transforming growth factor (TGF)‐β superfamily of signal molecules that mediate many diverse biological processes ranging from early embryonic tissue patterning to postnatal tissue homeostasis. BMPs trigger cell responses mainly through the canonical signaling pathway where intracellular
Xuelin, Li, Xu, Cao
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Heparin inhibits BMP‐2 osteogenic bioactivity by binding to both BMP‐2 and BMP receptor
Journal of Cellular Physiology, 2008AbstractHeparin demonstrates several kinds of biological activities by binding to various extracellular molecules and plays pivotal roles in bone metabolism. However, the role of heparin in the biological activity of bone morphogenetic protein (BMP) remains unclear.
Shin, Kanzaki +6 more
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Nature Genetics, 2001
Three years after MADH4 (also known as SMAD4) was identified as a gene critical to juvenile polyposis, BMPR1A, encoding a receptor in the same pathway, has been identified as another susceptibility gene. The TGFβ/BMP superfamily of molecules has not only been shown to be defective in neoplasia but also in the non-cancer developmental syndromes primary ...
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Three years after MADH4 (also known as SMAD4) was identified as a gene critical to juvenile polyposis, BMPR1A, encoding a receptor in the same pathway, has been identified as another susceptibility gene. The TGFβ/BMP superfamily of molecules has not only been shown to be defective in neoplasia but also in the non-cancer developmental syndromes primary ...
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BRAM1, a BMP receptor‐associated molecule involved in BMP signalling
Genes to Cells, 1998BackgroundTGF‐β superfamily members elicit signals through the stimulation of serine/threonine‐kinase receptors. Recently, molecules associated with several TGF‐β family receptors have been cloned. One such molecule, the immunophilin FKBP12, has been reported to interact with TGF‐β family type I receptors.
K, Kurozumi +5 more
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