Results 261 to 270 of about 272,370 (331)

Clinical Outcomes of Anorganic Bone Matrix Combined With a P-15 Osteogenic Cell-Binding Peptide (ABM/P-15) in One- and Two-Level Transforaminal Lumbar Interbody Fusion (TLIF): A Propensity-Matched Comparison. [PDF]

Cureus
Nishizawa M, Glassman SD, Djurasovic M, Crawford CH, Gum J, Dimar JR, Owens RK, Duncan A, Carreon L.   +8 more
europepmc   +1 more source

Effect of the Arg16Gly β2‐Adrenergic Receptor Polymorphism on Long‐Term Mepolizumab Response and Clinical Remission in Severe Eosinophilic Asthma: A Genotype‐Stratified, Multicenter Study

Allergy, EarlyView.
This study examines the association between the rs1042713 (Arg16Gly) polymorphism of the β2‐adrenergic receptor and the risk of severe eosinophilic asthma, as well as its influence on mepolizumab long‐term effectiveness and clinical remission. The Arg16 allele is associated with increased risk of severe disease and potentially diminished long‐term ...
Santi Nolasco, Evelina Fagone, Raffaele Campisi, Andrea Portacci, Giulia Scioscia, Corrado Pelaia, Angelantonio Maglio, Claudio Candia, Vitaliano Nicola Quaranta, Isabella Carrieri, Alessandro Saglia, Alessandro Vatrella, Girolamo Pelaia, Carlo Vancheri, Maria Pia Foschino Barbaro, Maria D'Amato, Giovanna Elisiana Carpagnano, Nunzio Crimi, Claudia Crimi, on behalf of the Southern Italy Network on Severe Asthma Therapy, Rossella Intravaia, Morena Porto, Pietro Impellizzeri, Maria Provvidenza Pistorio, Fabio Vignera, Andrea Alessia Nardo, Concetta Giannì, Silvano Dragonieri, Flogerta Sana, Valeria Pezzuto, Santina Ferulli, Massimo Triggiani, Roberta Parente, Pasquale Tondo, Piera Soccio, Donato Lacedonia, Luigi Ciampo, Antonio Franzese, Valeria Longobardi   +38 more
wiley   +1 more source

Emerging Strategies for Bioactive Agent-Loaded Xenogeneic Bone Scaffolds in Regenerative Medicine: A Comprehensive Review. [PDF]

Drug Des Devel Ther
Zhang J, Qin W, Yue W, Zhang W, Zhao Y, Xu G.   +5 more
europepmc   +1 more source

Mediation of Polygenic Asthma Risk Through Gene Expression

Allergy, EarlyView.
We apply published PRSs in African‐ancestry individuals and quantify the extent to which the PRS‐asthma relationship is mediated by clinical biomarkers and gene‐expression signatures of asthma. We found the best PRS to be the one derived using the largest sample size and including African‐ancestry individuals.
Rakesh Natarajan, Brooke Szczesny, Kanika Kanchan, Erika Esquinca, Meher Preethi Boorgula, Sameer Chavan, Monica Campbell, Wendy Lorizio, Ayo P. Doumatey, Alvaro A. Cruz, Harold Watson, Edward T. Naureckas, B. Louise Giles, Ganiyu Arinola, Olumide Sogaolu, Adegoke G. Falade, Nadia N. Hansel, Christopher O. Olopade, Charles N. Rotimi, R. Clive Landis, Camila A. Figueiredo, Eimear E. Kenny, Ingo Ruczinski, Andrew H. Liu, Carole Ober, Margaret A. Taub, Randi K. Johnson, Kathleen C. Barnes, Genevieve L. Wojcik, Rasika A. Mathias   +29 more
wiley   +1 more source

Inhibition of astrocyte BMP signaling alleviates neuroinflammation in experimental models of Parkinson's disease. [PDF]

Cell Death Discov
Li Y, Li Y, Hao J, Wang W, Su Z, Tian X, Wang H, Liu Q, Gao J, Geng D, Wang L.   +10 more
europepmc   +1 more source

Pain management after open thoracotomy 2025: procedure‐specific postoperative pain management (PROSPECT) recommendations

Anaesthesia, EarlyView.
Summary Introduction Adequate postoperative pain control is crucial for rehabilitation after open thoracotomy. The aim of this systematic review was to update the previous procedure‐specific postoperative pain management recommendations for patients undergoing open thoracotomy.
Adrien Lemoine, Anna Alber, Girish P. Joshi, Marc Van de Velde, Geertrui Dewinter, Esther Pogatzki‐Zahn, Marie‐Pierre Bonnet, on behalf of the PROSPECT Working Group of the European Society of Regional Anaesthesia and Pain Therapy, Eric Albrecht, Hélène Beloeil, Dario Bugada, Neel Desai, Geertrui Dewinter, Stephan Freys, Henrik Kehlet, Patricia Lavand'homme, Dileep Lobo, Eleni Moka, Esther Pogatzki‐Zahn, Johan Raeder, Narinder Rawal, Axel Sauter, Christopher Wu   +22 more
wiley   +1 more source

Emerging genomic biomarkers in diagnosis and classification of T-cell acute lymphoblastic leukemia. [PDF]

Hematology Am Soc Hematol Educ Program
Xu J, Teachey DT.
europepmc   +1 more source

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

Andrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos, Marie‐Pier Scott‐Boyer, Arnaud Droit, Robert S. Viger, Jacques J. Tremblay   +4 more
wiley   +1 more source

Predictive potential of hepatocyte growth factor and bone morphogenetic proteins in lymphatic metastasis of breast cancer. [PDF]

Transl Breast Cancer Res
Cong BB, Cao XS, Wang YS, Jiang WG, Ye L.   +4 more
europepmc   +1 more source