Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.Abstract Acute, traumatic meniscus tears are common and should be repaired whenever possible. However, the biological age of the patient, along with the specific tear morphology, may significantly influence the selection of the repair technique, expected clinical outcomes and the postoperative rehabilitation protocol.
Armin Runer +15 more
wiley +1 more source
Suppression of astrocyte BMP signaling improves molecular signatures and functional deficits in a fragile X syndrome mouse model. [PDF]
Nat CommunDeng J +10 more
europepmc +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Hedgehog and Bmp signaling pathways play opposing roles during establishment of the cardiac inflow tract in zebrafish. [PDF]
DevelopmentRobertson RA +6 more
europepmc +1 more source
Senotherapeutics for Knee Osteoarthritis
Medicinal Research Reviews, EarlyView.ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman +6 more
wiley +1 more source
Comparative analysis of BMP signaling in human ECFCs reveals vascular bed-dependent ALK2 expression. [PDF]
Vasc BiolGroßmann NZ +9 more
europepmc +1 more source
Recent Advances in Cryogel Applications for Musculoskeletal Regeneration
Medicinal Research Reviews, EarlyView.ABSTRACT Hydrogels have been widely used in tissue engineering due to their high‐water content and biocompatibility, yet their densely cross‐linked microstructure inherently limits cell infiltration, mass transport, and mechanical support. Cryogels, formed through partial freezing and crosslinking under subzero conditions, provide unique 3D macroporous
Dohee Kim +4 more
wiley +1 more source
To BMP or not to BMP - On BMP Signalling during Axis Formation in Mouse Gastruloids
La proteïna morfogenètica òssia 4 (BMP4), secretada pel teixit extraembrionari ectodèrmic, es considera essencial per a la gastrulació i la formació del eix corporal en embrions de ratolí. Tot i això, recentment, models in vitro basats en cèl·lules mare embrionàries de ratolí (mESC) han demostrat que les cèl·lules embrionàries, en absència de teixit ...
openaire +1 more source
The CHD Protein, Kismet, Restricts Synaptic BMP Signaling at Glutamatergic Synapses. [PDF]
Neurosci InsightsKlaustermeier RA +3 more
europepmc +1 more source
Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges
Neuroprotection, EarlyView.Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi +5 more
wiley +1 more source