Results 1 to 10 of about 148,190 (307)

Combinatorial Signal Perception in the BMP Pathway

Cell, 2017
Summary The Bone Morphogenetic Protein (BMP) signaling pathway comprises multiple ligands and receptors that interact promiscuously with one another, and typically appear in combinations.
Heidi Klumpe, Bogdan Bintu, Michael Elowitz   +2 more
exaly   +2 more sources

Gremlin1 preferentially binds to bone morphogenetic protein-2 (BMP-2) and BMP-4 over BMP-7 [PDF]

Biochemical Journal, 2015
Gremlin (Grem1) is a member of the DAN family of secreted bone morphogenetic protein (BMP) antagonists. Bone morphogenetic protein-7 (BMP-7) mediates protective effects during renal fibrosis associated with diabetes and other renal diseases. The pathogenic mechanism of Grem1 during diabetic nephropathy (DN) has been suggested to be binding and ...
Church, Rachel H., Krishnakumar, Arjun, Urbanek, Annika, Geschwinder, Stefan, Meneely, Julie, Bianchi, Alessandro, Basta, Barbro, Monaghan, Sean, Elliott, Christopher, Stromstedt, Maria, Ferguson, Neil, Martin, Finian, Brazil, Derek P.   +12 more
openaire   +4 more sources

BMP-2/6 Heterodimer Is More Effective than BMP-2 or BMP-6 Homodimers as Inductor of Differentiation of Human Embryonic Stem Cells [PDF]

PLoS ONE, 2010
Bone Morphogenetic Protein (BMP) signaling pathways are involved in differentiation of stem cells into diverse cell types, and thus BMPs can be used as main guidance molecules for in vitro differentiation of human stem cells.We have analyzed the ability ...
Yasuhiko Kawakami, Senyon Choe
exaly   +2 more sources

Comparison on batch anaerobic digestion of five different livestock manures and prediction of biochemical methane potential (BMP) using different statistical models

Waste Management, 2016
Lide Chen, Gopi Krishna Kafle
exaly   +2 more sources

BMP signaling in vascular biology and dysfunction

Cytokine and Growth Factor Reviews, 2016
An Zwijsen, Sabine Bailly, Petra Knaus
exaly   +2 more sources

Full-length transcriptome and analysis of bmp-related genes in Platypharodon extremus

Heliyon, 2022
Platypharodon extremus is an endemic species on the Qinghai–Tibet Plateau. As a secondary protected species in China, the basic genomic information of this species has not yet been reported.
Xiaoyun Wu, Quan Gong, Yeyu Chen, Ya Liu, Mingjiang Song, Feiyang Li, Pengcheng Li, Jiansheng Lai   +7 more
doaj   +1 more source

Simulation-optimization framework in urban flood management for historic and climate change scenarios

Journal of Water and Climate Change, 2022
A simulation-optimization framework is established by integrating Hydrologic Engineering Center Hydraulic Modeling System (HEC-HMS) for computation of runoff, siting tool EPA System for Urban Storm-water Treatment and Analysis INtegration (EPA-SUSTAIN ...
R. Madhuri, Y. S. L. Sarath Raja, K. Srinivasa Raju   +2 more
doaj   +1 more source

Completion of neural crest cell production and emigration is regulated by retinoic-acid-dependent inhibition of BMP signaling

eLife, 2022
Production and emigration of neural crest cells is a transient process followed by the emergence of the definitive roof plate. The mechanisms regulating the end of neural crest ontogeny are poorly understood. Whereas early crest development is stimulated
Dina Rekler, Chaya Kalcheim
doaj   +1 more source

Application of BMP in Bone Tissue Engineering

Frontiers in Bioengineering and Biotechnology, 2022
At present, bone nonunion and delayed union are still difficult problems in orthopaedics. Since the discovery of bone morphogenetic protein (BMP), it has been widely used in various studies due to its powerful role in promoting osteogenesis and ...
Liwei Zhu, Yu-Zhe Liu, Ao Wang, Zhengqing Zhu, You-Bin Li, Chen-Yi Zhu, Zhenjia Che, Tengyue Liu, He Liu, Lan-Feng Huang   +9 more
semanticscholar   +1 more source

Novel Indolyl-Benzimidazole Compounds Promote in vitro Wound Healing and Osteogenic Differentiation of Pluripotent Cells

Frontiers in Bioscience-Landmark, 2023
Background: Increasing or restoring Bone Morphogenetic Protein- (BMP-) signaling through administration of recombinant BMPs (rBMPs) has demonstrated therapeutic efficacy for treating bone fractures or to enhance repair following spinal surgeries. However,
Sheyda Najafi, Leonard Barasa, Jilian Maxine J. Frianela, Jawaher H. Alkhamisy, Sabesan Yoganathan, Jeanette C. Perron   +5 more
doaj   +1 more source