Results 11 to 20 of about 148,190 (307)
Quantitative analysis of signaling responses during mouse primordial germ cell specification
Biology Open, 2021 During early mammalian development, the pluripotent cells of the embryo are exposed to a combination of signals that drive exit from pluripotency and germ layer differentiation.
Sophie M. Morgani +1 more
doaj +1 more source
Water Science and Technology, 2023 There is an increasing interest in integrating aerobic granular sludge (AGS) technology into wastewater industries. Several projects are being performed to cultivate the aerobic granules for continuous flow reactors (AGS-CFR), while there is a scarcity ...
Salahaldeen Dababat +3 more
doaj +1 more source
Distinct Mesenchymal Cell Populations Generate the Essential Intestinal BMP Signaling Gradient
Cell Stem Cell, 2020 SUMMARY Intestinal stem cells (ISCs) are confined to crypt bottoms and their progeny differentiate near crypt-villus junctions. Wnt and bone morphogenic protein (BMP) gradients drive this polarity, and colorectal cancer fundamentally reflects disruption ...
Neil McCarthy +14 more
semanticscholar +1 more source
The Balance of Stromal BMP Signaling Mediated by GREM1 and ISLR Drives Colorectal Carcinogenesis
Gastroenterology, 2020 Background & AIMS Cancer-associated fibroblasts (CAFs), key constituents of the tumor microenvironment, either promote or restrain tumor growth.
Hiroki Kobayashi +35 more
semanticscholar +1 more source
A review of BMP and Wnt signaling pathway in the pathogenesis of pulmonary arterial hypertension
Clinical and Experimental Hypertension, 2022 Pulmonary arterial hypertension (PAH) is a chronic disease characterized by a progressive elevation in mean pulmonary arterial pressure. This occurs due to abnormal remodeling of small peripheral lung vasculature resulting in progressive occlusion of the
Zhihong Xin +10 more
doaj +1 more source
Fly, 2022 The Drosophila wing has been used as a model for studying tissue growth, morphogenesis and pattern formation. The wing veins of Drosophila are composed of two distinct structures, longitudinal veins and crossveins.
Hanna Antson +2 more
doaj +1 more source
Changes of BMP-2 and BMP-4 in early phase of sepsis [PDF]
Jichu yixue yu linchuang, 2022 Objective To study the change of serum bone morphogenetic protein (BMP)-2 and BMP-4 during the development of sepsis and its mechanisms. Methods Blood was collected for quantifying serum BMP-2 and BMP-4 from patients with sepsis (sepsis group), patients ...
WEN Yan, LIN Jin-can, HUANG Ying-hong, XIAO Wen-biao, ZHANG Min-wei, LIN Jian-dong
doaj +1 more source
Embryonic Patterning: To BMP or Not to BMP, That Is the Question [PDF]
Cell, 1997 Although some progress in understanding the molecular mechanisms of early embryogenesis has been made, a few outstanding issues remain to be clarified. Of particular interest is whether dorsal–ventral patterning of the endoderm is also controlled by BMP signaling.
openaire +2 more sources
Bone Research, 2016 Transforming growth factor-beta (TGF-β) and bone morphogenic protein (BMP) signaling has fundamental roles in both embryonic skeletal development and postnatal bone homeostasis.
Mengrui Wu, Gui-Qian Chen, Yi-Ping Li
semanticscholar +1 more source
Morphogenesis and axis specification occur in parallel during optic cup and optic fissure formation, differentially modulated by BMP and Wnt [PDF]
Open Biology, 2019 Optic cup morphogenesis is an intricate process. Especially, the formation of the optic fissure is not well understood. Persisting optic fissures, termed coloboma, are frequent causes for congenital blindness.
Priska Eckert +4 more
doaj +1 more source