Results 191 to 200 of about 905,740 (294)

Drosophila Dpp and BMP signaling directly regulates dpp transcription for optimal ligand production. [PDF]

Development
Zhang Y, Feng Y, Ye X, Lin Y, Zeng L, Luo Y, Zhou L, Shen C, Hu W, Yan D, Lin X.   +10 more
europepmc   +1 more source

Epigenetic Regulation of Liver Fibrosis: Mechanisms and Therapeutic Implications

Portal Hypertension &Cirrhosis, EarlyView.
This review synthesizes the epigenetic mechanisms—DNA methylation, histone modifications, and non‐coding RNAs—that drive hepatic stellate cell activation and the progression of liver fibrosis. It further evaluates emerging therapeutic strategies targeting these epigenetic regulators, including DNA methyltransferase and histone deacetylase inhibitors ...
Maryam Jadid Tavaf, Mahboobeh Ebrahimi Varkiani, Saeid Abroun, Pedram Asadi‐Sarabi, Shukoofeh Torabi, Elham Rismani, Mohammad Majd Hammour, Andreas K. Nüssler, Massoud Vosough   +8 more
wiley   +1 more source

Beclin1 deficiency unlocks cardiac lineage commitment through convergent Wnt and BMP signaling activation. [PDF]

Stem Cell Res Ther
Xiang L, Jia Z, Yu Z, Wang L, Cai H, Zhang T, Lu Z, Wang L.   +7 more
europepmc   +1 more source

Current Trends and Future Prospects of Integrating Electrospinning With 3D Printing Techniques for Mimicking Bone Extracellular Matrix Scaffolds

Journal of Polymer Science, Volume 63, Issue 6, Page 1481-1504, 15 March 2025.
ABSTRACT This article presents a review of the recent findings on the combination of electrospun nanofibers and three‐dimensional (3D)‐printed structures for extracellular matrix (ECM) scaffolds for bone tissue engineering. We explore the synergy between electrospinning (ES), which produces highly porous, fibrous structures from materials like collagen
Kardo Khalid Abdullah, Kolos Molnár
wiley   +1 more source

Natural Products Exhibit Therapeutic Potential in Treating Rheumatoid Arthritis by Targeting the PI3K/Akt Signaling Pathway

Phytotherapy Research, EarlyView.
This review summarizes how natural products, mainly including flavonoids, terpenoids, alkaloids, and polyphenols alleviate RA via PI3K/Akt pathway, regulating inflammation, proliferation, apoptosis, angiogenesis, and osteoclast differentiation. The figure was created by Figdraw (https://www.figdraw.com/#/).
Haishuo Ren, Yige Wang, Wenjing Ma, Omachi Daniel Ogaji, Shujing Chen, Kunze Du, Xuemi Zhang, Bo Xu, Shanxing Zhai, Shiming Fang, Yanxu Chang   +10 more
wiley   +1 more source

Regulation of TGF-β and BMP Signaling by Natural Triterpene Compounds in Pulmonary Arterial Hypertension (PAH). [PDF]

Curr Issues Mol Biol
Sener SO, Shaha S, İşcan SG, Ozgen U, Baran MY, Nalcaoğlu A, Nasim MT.   +6 more
europepmc   +1 more source

Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential

Phytotherapy Research, EarlyView.
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi, Sina Vossoughinia, Zahra Yazdanpanah, Hossein Sobhani, Jalileh Jalali, Mahboobeh Ghasemzadeh Rahbardar   +5 more
wiley   +1 more source

TGF-β/BMP signaling in skeletal biology: molecular mechanisms, regulatory networks, and therapeutic implications in development, regeneration, and disease. [PDF]

Bone Res
Liao J, Wu T, Zhang Q, Shen P, Huang Z, Wang J, Zhang P, Lin S, Pi J, Zhang N, Wang H, Chen G.   +11 more
europepmc   +1 more source

How AI and Digital Technologies Can Enhance Sustainable Livestock Manure Management: An Overview From Treatment to Distribution

Sustainable Development, EarlyView.
ABSTRACT Sustainable livestock manure management sits at the nexus of climate, nutrient circularity and water quality. This review explores how artificial intelligence (AI) and digital platforms are used across four management stages, that is, treatment, storage, valorisation and distribution, and figures out where integration fails to deliver ...
Zhan Shi, Feihong Liang, Francesco Marinello, Andrea Pezzuolo   +3 more
wiley   +1 more source

BMP9 attenuates microgravity-related disuse osteoporosis by modulating TGFβ and BMP signaling. [PDF]

NPJ Microgravity
Zhao H, Yang M, Liu Y, Tu X, Shao G.
europepmc   +1 more source