Results 1 to 10 of about 43,073 (212)

Risk of thyroid dysfunction associated with mRNA and inactivated COVID-19 vaccines: a population-based study of 2.3 million vaccine recipients [PDF]

BMC Medicine, 2022
Background In view of accumulating case reports of thyroid dysfunction following COVID-19 vaccination, we evaluated the risks of incident thyroid dysfunction following inactivated (CoronaVac) and mRNA (BNT162b2) COVID-19 vaccines using a population-based
Carlos King Ho Wong, David Tak Wai Lui, Xi Xiong, Celine Sze Ling Chui, Francisco Tsz Tsun Lai, Xue Li, Eric Yuk Fai Wan, Ching Lung Cheung, Chi Ho Lee, Yu Cho Woo, Ivan Chi Ho Au, Matthew Shing Hin Chung, Franco Wing Tak Cheng, Kathryn Choon Beng Tan, Ian Chi Kei Wong   +14 more
doaj   +2 more sources

Antibody and B‐Cell Responses to PHH‐1V81 XBB.1.16‐Adapted SARS‐CoV‐2 Booster Vaccination Are Associated With Variant Neutralization [PDF]

J Med Virol
ABSTRACT Immune escape by SARS‐CoV‐2 emerging variants jeopardizes vaccine effectiveness, necessitating new immunization strategies. Here, we assessed the antibody B‐cell response in 40 individuals receiving either the PHH‐1V81 XBB.1.16‐ or BNT162b2 XBB.1.5‐adapted vaccine boosters.
Torres C, Jiménez A, Deulofeu M, Prenafeta A, Dobaño C, Moncunill G, Ferrer L, Molinos‐Albert L.   +7 more
europepmc   +2 more sources

A 22 month prospective assessment of neutralizing and IgG antibody levels against SARS-CoV-2 variants following homologous and heterologous BNT162b2 boosting [PDF]

Scientific Reports
This 22-month cohort study investigated the durability and dynamics of humoral immune responses in 327 Malaysians vaccinated with either CoronaVac or BNT162b2 in early 2021, monitored up to 52 weeks following a BNT162b2 booster. Using the ImmuSAFE™ COVID 
Aini Syahida Mat Yassim, Anis Atifah Mohd Hisham, Nik Nur Atiqah Nik Daud, Nur Diana Anuar, Ti-Myen Tan, Rapeah Suppian, Mat Jusoh Siti Asmaa, Amiratul Aifa Mohamad Asri, Maryam Azlan, Nur Suhaila Idris, Rosediani Muhamad, Mohd Nor Norazmi   +11 more
doaj   +2 more sources

Safety of BNT162b2 mRNA COVID‐19 Vaccine Batches: A Nationwide Cohort Study [PDF]

Pharmacoepidemiol Drug Saf
ABSTRACT Objectives The safety of the BNT162b2 mRNA COVID‐19 vaccine has been extensively evaluated since the global rollout began. While serious adverse events are rare, safety issues continue to arise. This study evaluates the claim that earlier small vaccine batches were associated with higher rates of serious adverse events compared to later ...
Hviid A, Svalgaard I.
europepmc   +2 more sources

Safety and Immunogenicity of Monovalent Omicron KP.2-Adapted BNT162b2 COVID-19 Vaccine in Adults: Single-Arm Substudy from a Phase 2/3 Trial [PDF]

Infectious Diseases and Therapy
Introduction COVID-19 continues to cause substantial health burden, particularly among vulnerable populations. Vaccines remain a vital tool in preventing severe disease outcomes. As the causative pathogen, severe acute respiratory syndrome coronavirus 2 (
Oyeniyi Diya, Juleen Gayed, Francine S. Lowry, Hua Ma, Vishva Bangad, Federico Mensa, Jing Zou, Xuping Xie, Yanping Hu, Mark Cutler, Todd Belanger, David Cooper, Xia Xu, Robin Mogg, Özlem Türeci, Uǧur Şahin, Kena A. Swanson, Kayvon Modjarrad, Annaliesa S. Anderson, Alejandra Gurtman, Nicholas Kitchin   +20 more
doaj   +2 more sources

Safety and immunogenicity of fractional COVID-19 vaccine doses in Nigerian adults: A randomized non-inferiority trial. [PDF]

Sci Rep
Fractional dosing of vaccines is a viable strategy to extend COVID-19 vaccine supplies in resource-constrained settings. We did a triple-blinded, multi-site, randomized non-inferiority trial in Nigeria (PACTR202206754734018).
Salako A, Musa A, Ige F, Abdullahi A, James A, Ekama S, Odubela O, Idigbe I, Ajibaye O, Altaf M, Adeneye K, Akinsolu FT, Olojo I, Okwuraiwe A, Egharevba H, Ekpenyong M, Elemuwa U, Ezenyi I, Bitrus F, Odubela O, Oba A, Idris G, Yusuf J, Akande I, Nwaiwu S, Omale L, Oyewunmi O, Agbabiaka A, Eyinade O, Ogunwale J, Garba A, Bello Y, Musa B, Ezejiofor O, Ejiro B, Iwalokun B, Rosenzweig L, Adigwe O, Adeyeye C, Shuaib F, Wicek W, Hamada Y, Ezechi O, Gupta R, Salako B.   +44 more
europepmc   +3 more sources

Effectiveness of a third dose of COVID-19 vaccines against delta variant of SARS-COV-2: A Serbian cohort study [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2023
Introduction/Objective. The duration of vaccine-induced protection against SARS-CoV-2 is shown to be limited. The aim of this study was to assess vaccine effectiveness (VE) of a third dose of four different COVID-19 vaccines during Delta variant ...
Đorđević Nataša, Matić Sanja, Milovanović Dragan, Stefanović Srđan, Popović Suzana, Todorović Danijela, Đurđević Predrag, Sazdanović Predrag, Antić Vasilije, Lončar Slavica, Bukumira Slavica, Radenković Marko, Šusteršić Tijana, Filipović Nenad, Baskić Dejan   +14 more
doaj   +1 more source

Variety of Antibody Responses to BNT162b2 and BBIBP-CorV Vaccinations Against COVID-19 Infections in Baghdad and Fallujah, Iraq

UKH Journal of Science and Engineering, 2023
The huge impact of COVID-19 worldwide led to the rapid development of vaccines with inadequate data about its longevity, effectivity, and safety. This study aims to evaluate the effectiveness and safety of COVID-19 vaccines available in Iraq and to ...
Mohammed A. Hamad, Mohammed N. Abed, Najemaddin A. Hamad, Mariam A. Abdul-Latif, Nehal A. Mohammed, Aya N. Abdul-Razaq, Rawaa A. Muhammed   +6 more
doaj   +1 more source

Evaluation of the BNT162b2 Covid-19 Vaccine in Children 5 to 11 Years of Age [PDF]

, 2022
Background: Safe, effective vaccines against coronavirus disease 2019 (Covid-19) are urgently needed in children younger than 12 years of age.Methods: A phase 1, dose-finding study and an ongoing phase 2–3 randomized trial are being conducted to ...
Barnett, E. D., Belanger, T. J., Cooper, D., Cunliffe, L., Domachowske, J. B., Dormitzer, P. R., Frenck, R. W., Jr., Gruber, W. C., Gurtman, A., Jansen, K. U., Kitchin, N., Koury, K., Kuchar, E., Lagkadinou, E., Lockhart, S., Ma, H., Maldonado, Y., Mather, S., Munjal, I, Munoz, F. M., Pahud, B. A., Paulsen, G. C., Perez, J. L., Rojo, P., Rämet, M., Sabharwal, C., Sarwar, U. N., Simoes, E. A. F., Swanson, K. A., Talaat, K. R., Tureci, O., Walter, E. B., Xu, X.   +32 more
core   +1 more source

Could Prior COVID-19 Affect the Neutralizing Antibody after the Third BNT162b2 Booster Dose: A Longitudinal Study [PDF]

, 2023
Aşılama, devam eden COVID-19 salgını sırasında hastalığın yayılmasını önlemek için temel bir halk sağlığı önlemidir. Konakçının geliştirdiği immün yanıt veya aşının oluşturduğu immünolojik yanıtın devam etmesi, salgının gidişatını değiştirebileceği için ...
Buber, Suleyman, Demirci, Mehmet, Erdem, Mustafa Genco, Kocazeybek, Bekir Sami, Ünlü, Özge   +4 more
core   +2 more sources