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Influence of a Heterologous (ChAdOx1-nCoV-19/BNT162b2) or Homologous (BNT162b2/BNT162b2) Vaccination Regimen on the Antibody and T Cell Response to a Third Vaccination with BNT162b2

open access: yesVaccines, 2022
Emerging numbers of SARS-CoV-2 infections are currently combated with a third vaccination. Considering the different vaccination regimens used for the first two vaccine doses, we addressed whether the previous vaccination influences the immune response ...
Geßner, Reinhard   +11 more
core   +5 more sources

Immunogenicity and efficacy of heterologous ChAdOx1-BNT162b2 vaccination [PDF]

open access: yesNature, 2021
Following severe adverse reactions to the AstraZeneca ChAdOx1-S-nCoV-19 vaccine1,2, European health authorities recommended that patients under the age of 55?years who received one dose of ChAdOx1-S-nCoV-19 receive a second dose of the Pfizer BNT162b2 ...
Lina, Bruno   +24 more
core   +6 more sources

Anti-spike antibody trajectories in individuals previously immunised with BNT162b2 or ChAdOx1 following a BNT162b2 booster dose [PDF]

open access: yesWellcome Open Research, 2022
Background: The two most common SARS-CoV-2 vaccines in the UK, BNT162b2 (Pfizer-BioNTech) and ChAdOx1 nCoV-19 (Oxford-AstraZeneca), employ different immunogenic mechanisms.
Fong, Wing Lam Erica   +29 more
core   +5 more sources

Heterologous ChAdOx1-BNT162b2 vaccination in Korean cohort induces robust immune and antibody responses that includes Omicron

open access: yesiScience, 2022
Summary: Heterologous ChAdOx1-BNT162b2 vaccination induces a stronger immune response than BNT162b2-BNT162b2. Here, we investigated the molecular transcriptome, germline allelic variants of immunoglobulin loci, and anti-Omicron antibody levels in 46 ...
Hye Kyung Lee   +8 more
doaj   +2 more sources

Adverse Reactions after BNT162b2 Messenger RNA Vaccination for Coronavirus Disease 2019 in Healthcare Workers Compared with Influenza Vaccination

open access: yesVaccines, 2023
This study aimed to compare adverse reactions following BNT162b2 and influenza vaccinations in healthcare workers. This study included healthcare workers who received the BNT162b2 vaccine and/or inactivated influenza vaccine, quadrivalent (IIV4), on 18 ...
A-Sol Kim   +5 more
doaj   +2 more sources

Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line

open access: yesCurrent Issues in Molecular Biology, 2022
Preclinical studies of COVID-19 mRNA vaccine BNT162b2, developed by Pfizer and BioNTech, showed reversible hepatic effects in animals that received the BNT162b2 injection.
Markus Aldén   +6 more
doaj   +3 more sources

Acute myocarditis following administration of BNT162b2 vaccine

open access: yesIDCases, 2021
The wide use of vaccines was linked with rare but serious complications in adults, causing a global concern. Here, we describe a young male patient, who presented with acute myocarditis, three days after the second dose of BNT162b2 ...
Mawahib Elhassan   +9 more
core   +4 more sources

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine.

open access: yesNew England Journal of Medicine, 2020
BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the resulting coronavirus disease 2019 (Covid-19) have afflicted tens of millions of people in a worldwide pandemic.
Nell, Haylene   +41 more
core   +3 more sources

Booster Vaccination with BNT162b2 Improves Cellular and Humoral Immune Response in the Pediatric Population Immunized with CoronaVac

open access: yesVaccines
The SARS-CoV-2 Omicron variant and its sublineages continue to cause COVID-19-associated pediatric hospitalizations, severe disease, and death globally. BNT162b2 and CoronaVac are the main vaccines used in Chile.
Diego A. Díaz-Dinamarca   +15 more
doaj   +2 more sources

Beyond neutralization for BNT162b2 mRNA vaccination [PDF]

open access: yesCell Host & Microbe, 2021
Mounting a robust immune response against SARS-CoV-2 requires neutralization as well as effector T cell functions. In this issue of Cell Host Microbe, Tauzin et al. characterize the humoral and T cell responses after a single dose of BNT162b2 mRNA vaccine in individuals with or without previous exposure to SARS-CoV-2.
Damani-Yokota, Payal   +2 more
openaire   +2 more sources

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