Results 131 to 140 of about 9,352,890 (302)

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

open access: yesMolecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis   +20 more
wiley   +1 more source

Columbia Accident Investigation Board Report: Volume 2. CAIB Technical Documents Cited in the Report

open access: yes, 2003
Second volume of the final report produced by the Columbia Accident Investigation Board including appendices on reports produced by NASA and other organizations in support of the investigation into the February 1, 2003 destruction of the Space Shuttle ...
Columbia Accident Investigation Board
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Annual report / Katherine Hospital Management Board 1995/96

open access: yes, 1996
Please find attached the 1995/96 Annual Report of the Katherine Hospital Management Board, in accordance with Section 25 ( 1) of the Hospital Management Board ...

core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Columbia Accident Investigation Board Report: Volume 3. Other Technical Documents Cited in the Report

open access: yes, 2003
Third volume of the final report produced by the Columbia Accident Investigation Board including assorted technical documents produced by NASA and other organizations in support of the Board's inquiry into the February 1, 2003 destruction of Space ...
Columbia Accident Investigation Board
core  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Agenda Book, Meeting of the Board of Visitors, February, 2015

open access: yes, 2015
The Board of Visitors Agenda Book from the February 2015 meeting. The book includes Committee Meeting Schedule, Alumni Relations, Audit and Compliance, Athletics, Academic Affairs, Student Affairs, Administration, Buildings & Grounds ...
College of William and Mary. Board of Visitors
core  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Other title: Senate Bill 555 - Testimony on Behalf of the Citizens' Utility Ratepayer Board by David Springe, Consumer Counsel, Citizens' Utility Ratepayer Board

open access: yes, 2008
application/pdf; "February 14, 2008."; Testimony before the Kansas Legislature, Senate Utilities Committee, presented by David Springe, Consumer Counsel, Citizens' Utility Ratepayer Board.Testimony regarding Senate Bill 555.
Springe, David.
core   +1 more source

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