Results 151 to 160 of about 9,352,890 (302)

Report of the Business Manager of the State Board of Administration; Other title: Business Manager's Report

, 1916
1st (1916-1918)-[11th (1936/38)?]; Though some reports were published separately most of the reports were bound with the corresponding Biennial reports of the State Board of Administration.; Reports were approved by the State Board of ...
Kansas State Board of Administration. Business Manager
core  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

A Randomized Phase 3 Study to Evaluate the Safety, Tolerability, and Immunogenicity of the Bivalent RSVpreF Vaccine in Older Adults in Korea. [PDF]

Vaccines (Basel)
Choi WS, Quan K, Baber JA, Jaques A, van Rensburg KJ, Li W, Cutler MW, Kalinina EV, Anderson AS, Swanson KA, Gurtman A, Munjal I, Jeongwol C3671053 Clinical Trial Group.   +12 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Fidanacogene Elaparvovec Gene Therapy: Budesonide Treatment of a Late Decline in Factor IX Expression in a Patient with Hemophilia B. [PDF]

Int J Mol Sci
Herbst K, Pezeshkpoor B, Klein C, Albert T, Lutz P, Strassburg C, Spengler U, Goldmann G, Oldenburg J.   +8 more
europepmc   +1 more source

Biennial Reports [penal and correctional] ; Biennial Report, Board of Administration Corrective Institutions (1916-1918)

, 1918
Reports for 1932/34-1936/38 are found in the ninth to eleventh biennial reports of the State Board of Administration. Includes reports of the State penitentiary, Lansing, State industrial reformatory, Hutchinson, and State industrial farm for women ...
Kansas State Board of Administration.
core  

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Development of a national outpatient parenteral antimicrobial therapy (OPAT) pathway for skin and soft tissue infections in Scotland. [PDF]

JAC Antimicrob Resist
Seaton RA, Vallance C, White B, Esiovwa R, Robb F, Mooney G, Rigby D, Mackintosh CL, MacDonald A, Kerr F.   +9 more
europepmc   +1 more source