Results 161 to 170 of about 9,352,890 (302)

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Inverse Association Between Regional Availability of Board-Certified Fellows of the Japan Gastroenterological Endoscopy Society and Colorectal Cancer Mortality in Japan: An Ecological Analysis. [PDF]

JGH Open
Inoki K, Rahman M, Mizuno S, Suzuki N, Nakatani S, Kikuchi K, Katagiri A, Yoshida H, Kakushima N.   +8 more
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Expression of HDAC2 and HDAC8 in the airways of COPD patients is associated with responsiveness to ICS: insights from the HISTORIC study. [PDF]

Eur Respir J
Papakonstantinou E, Nowak M, Savic Prince S, Soriano D, Grize L, Frye BC, Fähndrich S, Koelzer VH, Stolz D.   +8 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Vasculitis and risk of bronchiectasis in alpha-1 antitrypsin deficiency subjects from the EARCO registry. [PDF]

Eur Respir J
Alluhibi R, Heyer-Chauhan N, Marshall A, Lomas DA, Torres-Duran M, Turner AM, Tanash H, Rodríguez-García C, Barrecheguren M, Corsico A, López-Campos JL, Jensen JS, Chapman KR, Lara B, Rodriguez-Hermosa JL, Bartošovská E, Mornex JF, Bunel-Gourdy V, Miravitlles M, Hurst JR.   +19 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

PubNavigator Activity to Promote Science Argumentation in Introductory Biology. [PDF]

Integr Org Biol
Marroquín-Flores RA, Campbell MA, Grimes SP, Limeri LB.   +3 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

NeuroTest: a benchtop testbed for evaluating sensing-capable electrophysiology and neurostimulation systems. [PDF]

J Neural Eng
Jk M, Cho H, Benjaber M, Tj D, As W, Ja H.   +5 more
europepmc   +1 more source