Results 131 to 140 of about 4,351,903 (305)
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
, 1918 Reports for 1932/34-1936/38 are found in the ninth to eleventh biennial reports of the State Board of Administration. Includes reports of the State penitentiary, Lansing, State industrial reformatory, Hutchinson, and State industrial farm for women ...
Kansas State Board of Administration.
core
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
, 2019 "January 30, 2019."; Presentation before the Kansas Legislature, Senate Utilities Committee, by David Nickel, Consumer Counsel, Citizens' Utility Ratepayer Board."CURB appreciates the opportunity to respond to the Rate Study furnished by the Staff of ...
Nickel, David W.
core +1 more source
Columbia Accident Investigation Board Report: Volume 2. CAIB Technical Documents Cited in the Report
, 2003 Second volume of the final report produced by the Columbia Accident Investigation Board including appendices on reports produced by NASA and other organizations in support of the investigation into the February 1, 2003 destruction of the Space Shuttle ...
Columbia Accident Investigation Board
core
, 2003 application/pdf; "February 18, 2003."; Testimony before the Kansas Legislature, House Utilities Committee, presented by David Springe, Consumer Counsel, Citizens' Utility Ratepayer Board.Testimony in opposition to House Bill 2374. The Citizens'
Springe, David.
core +1 more source
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
, 2003 Third volume of the final report produced by the Columbia Accident Investigation Board including assorted technical documents produced by NASA and other organizations in support of the Board's inquiry into the February 1, 2003 destruction of Space ...
Columbia Accident Investigation Board
core
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source