Results 111 to 120 of about 4,351,903 (305)
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Dublin Board of Public Health MINUTES of PROCEEDINGS From 1st April, 1931, to 31st March, 1932.
, 1932 Dublin Board of Public Health MINUTES of PROCEEDINGS From 1st April, 1931, to 31st March ...
Dublin Board of Public Health
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Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Progress report, Nemaha County Planning Board
, 1938 "August, 1938.", Reproduced from typewritten copy.; "First of a series of publications which will be issued from time to time on subdivisional planning."--Foreword.Nemaha County Planning Board -- Foreword -- Table Of Contents -- Introduction -- General ...
Nemaha County Planning Board (Kan.)
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, 2003 Fifth volume of the final report produced by the Columbia Accident Investigation Board including documents produced by NASA and other organizations that were provided to the Columbia Accident Investigation Board in support of its inquiry into the ...
Columbia Accident Investigation Board
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Annual Report 2021 Part 2 | Corporate Governance and Financial Statements
, 2023 The Board is responsible for keeping adequate accounting records which disclose, with reasonable accuracy at any time, its financial position and enables it to ensure that the financial statements comply with Article 27 of the Health Research Board ...
Health Research Board
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Board of Nursing and the rule making process a guide to public participation
, 2005 Title from PDF cover (i.e. p. [1]) (viewed Aug. 11, 2005).; "Publication date: 06/05"--P. 4 of cover (i.e. p. [12]).; Harvested from the web on 8/15/05Mission -- Rule making authority -- Rule review timeline -- Rule review process -- Adopting, revising ...
Ohio Board of Nursing
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